Results 101 to 110 of about 875,259 (309)

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Dynamic Properties of Coupled Tube-Array Structures with the Axial Loads

Latin American Journal of Solids and Structures
The tube-array structures coupled both with the fluid and the axial load is focused. In a heat exchanger, the tubes are frequently affected by cold and hot fluid shock waves. Thus, tubes are often found to be vibrated and even to be worn out.
Bo-Wun Huang, Pu-Ping Yu, Jung-Ge Tseng
doaj   +1 more source

Damage tolerance analysis of aircraft reinforced panels

Fracture and Structural Integrity, 2013
This work is aimed at reproducing numerically a campaign of experimental tests performed for the development of reinforced panels, typically found in aircraft fuselage.
F. Carta, A. Pirondi
doaj   +1 more source

Concepts for improving the damage tolerance of composite compression panels [PDF]

The residual strength of specimens with damage and the sensitivity to damage while subjected to an applied inplane compression load were determined for flatplate specimens and blade-stiffened panels. The results suggest that matrix materials that fail by
Rhodes, M. D., Williams, J. G.
core   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

Biomechanical and Injury Tolerance Analysis of Tibial Movement Under Different Postures and Impact Loads

Applied Sciences
The lower limbs play an important role in daily human activities. Therefore, a 3D tibial model is constructed, and finite element analysis is performed to investigate the biomechanical characteristics and injury tolerance of lower limb flexion movement ...
Lei Liu, Qian Qian, Hengjia Liu, Hongyan Liu, Jong-Chul Park   +4 more
doaj   +1 more source

Estimating Consumersï¾’ Valuation of Organic and Cosmetically Damaged Apples [PDF]

A mixed probit model was applied to survey data to analyze consumersï¾’ willingness to buy apples with cosmetic damage caused by the sooty blotch and flyspeck (SBFS) disease complex.
Bonett, Douglas, Gleason, Mark L., Jensen, Helen H., Mueller, Daren S., Nonnecke, Gail R., Yue, Chengyan   +5 more
core  

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Developments in impact damage modeling for laminated composite structures [PDF]

Damage tolerance is the most critical technical issue for composite fuselage structures studied in the Advanced Technology Composite Aircraft Structures (ATCAS) program.
Avery, William B., Dost, Ernest F., Lin, Kuen Y., Swanson, Gary D.   +3 more
core   +1 more source