Results 51 to 60 of about 355,992 (315)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Metals, 2019 The corrosion behavior of cemented carbides with binders of different chemical nature (Co and Ni) and carbides with distinct mean grain size (ultrafine and coarse) was studied. The investigation also included corrosion media (acidic and neutral solutions
Yafeng Zheng +4 more
doaj +1 more source
Comparison of Riveted Panel and Integral Panel for Damage Tolerance by using FEA [PDF]
, 2014 Damage tolerance capability refers to the load carrying capacity of a damaged structure. In an aircraft metallic structure damage is the fatigue crack. The presence of a fatigue crack reduce the load carrying capacity of a structure.
Srinivas, K.R., Shantharaja, M.
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Discussions on some problems of full-scale aircraft fatigue test
Hangkong gongcheng jinzhanFull-scale aircraft fatigue test is a large, complex and long-lasting ground verification test required by the specification to sustain aircraft structural integrity program and meet airworthiness requirements.
ZHANG Lixin
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
AGING AIRCRAFT STRUCTURES LIFE TIME
Научный вестник МГТУ ГА, 2017 Analysis of US and Russia Regulations on fatigue and damage tolerance of transport aircraft structures is given. The methods to provide the safe operation of aging aircraft in Russia are presented for cases of multiple site damages, corrosion and ...
B. G. Nesterenko, G. I. Nesterenko
doaj
Modelling of impact damage and permanent indentation on laminate composite plate [PDF]
, 2010 This paper deals with impact damage and permanent indentation modelling. A model enabling the formation of damages developing during a low velocity / low energy impact test on laminate composite panels has been elaborated.
Barrau, Jean-Jacques +2 more
core
Mechanical properties and damage tolerance of Y2SiO5
, 2008 Y2SiO5 has potential applications as functional-structural ceramic and environmental/thermal barrier coating material. As an important grain-boundary phase in the sintered Si3N4, it also influences the mechanical and dielectric performances of the host ...
Wang, J., Zhou, Y., Sun, Ziqi, Li, M.
core +1 more source
Stress intensity factor solutions for cracks in railway axles
, 2022 S.764-792The aim of this paper is a collection of stress intensity factor solutions for cracks in railway axle geometries which the authors of the present special issue developed and/or used for damage tolerance analyses.
Madia, M. +5 more
core +1 more source