Results 61 to 70 of about 355,992 (315)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Failure analysis of CFRP laminates subjected to Compression After Impact: FE simulation using discrete interface elements [PDF]
, 2013 This paper presents a model for the numerical simulation of impact damage, permanent indentation and compression after impact (CAI) in CFRP laminates.
Bouvet, Christophe +2 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Among-population variation in tolerance to larval herbivory by Anthocharis cardamines in the polyploid herb Cardamine pratensis. [PDF]
PLoS ONE, 2014 Plants have two principal defense mechanisms to decrease fitness losses to herbivory: tolerance, the ability to compensate fitness after damage, and resistance, the ability to avoid damage.
Malin A E König +3 more
doaj +1 more source
Ischemic Tolerance—A Way to Reduce the Extent of Ischemia–Reperfusion Damage
Cells, 2023 Individual tissues have significantly different resistance to ischemia–reperfusion damage. There is still no adequate treatment for the consequences of ischemia–reperfusion damage.
Rastislav Burda +2 more
doaj +1 more source
Assessment of Damage Tolerance and Reliability for Ceramics
Journal of the Society of Materials Science, Japan, 2001 The risk of fracture does exist even in the carefully designed ceramic components under excess stress unexpected in design procedure such as high stresses caused by restraining the deformation at the contact region of the component. To assess the safety and the reliability of ceramics components under such circumstances, it is indispensable to take the
SUZUKI, Akihiko, BABA, Hidenari
openaire +3 more sources
Damage tolerant wing-fuselage integration structural design applicable to future BWB transport aircraft [PDF]
, 2009 Wing joint design is one of the most critical areas in aircraft structures. Efficient and damage tolerant wing-fuselage integration structure, applicable to the next generation of transport aircraft, will facilitate the realisation of the benefits ...
Sodzi, P.
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Cryogenic 3D printing of damage tolerant hierarchical porous ceramics
International Journal of Extreme ManufacturingFabricating damage tolerant porous ceramics with efficient energy absorption and impact-resistant capability has been a challenge because of the brittle nature of ceramic materials.
Zheng Zhu +11 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source