Results 101 to 110 of about 670,121 (313)

Spatially random modulus and tensile strength : Contribution to variability of strain, damage, and fracture in concrete

, 2021
Publisher Copyright: © The Author(s) 2021. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.This paper explores the computational modeling of nonlocal strain, damage, and fracture in concrete, considering the isolated contribution of two ...
Niiranen, Jarkko, Castillo, Daniel, Nguyen, Tuan H.A.   +2 more
core   +1 more source

Experimental Investigation on the Mechanisms of Fiber Bragg Gratings to Monitor the Failure Processes of Pre-Cracked Sandstone Specimens

Applied Sciences
Real-time monitoring of internal fracture evolution in fractured rock masses using fiber Bragg grating (FBG) technology can help mitigate geotechnical hazards.
Zesheng Zhang, Shiming Wei, Hua Nan
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Incremental localized boundary-domain integro-differential equations of elastic damage mechanics for inhomogeneous body

, 2006
Copyright @ 2006 Tech Science PressA quasi-static mixed boundary value problem of elastic damage mechanics for a continuously inhomogeneous body is considered.
Mikhailov, SE
core  

Fatigue crack growth rates under variable amplitude load spectra containing tensile underloads [PDF]

, 2003
An extensive research program was performed to investigate the load interaction effect of the combined action of small amplitude high R ratio cycles and large amplitude low R ratio underloads on the crack growth of large cracks.
Zitounis, Vasilios
core  

Oriented damage in ductile sheets: Constitutive modeling and numerical integration

, 2007
Thermodynamics with internal variables provides a framework for constitutive modeling of elasto-plastic deformations. Within the scope of the theory, constitutive and evolution equations for ductile, elasto-plastic materials with mixed (isotropic and ...
Mattiasson, Kjell,, Omerspahic, Edin, Omerspahic, Edin,, Mattiasson, Kjell, Kjell Mattiasson, Edin Omerspahic   +5 more
core   +1 more source

Damage and dynamic characteristics of basalt under single-sided microwave irradiation

河南理工大学学报. 自然科学版
ObjectivesThe current indoor experiments on microwave-assisted mechanical rock breaking typically involve placing the sample directly in the microwave cavity for full exposure.
Dai Jun, Liu Boyuan, Yang Qingqing
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Experimental Study on Mechanical Deformation and Energy Evolution of Deep Coal Under Complex Stress Paths

Applied Sciences
This study proposes a novel cyclic stress path with simultaneous axial and confining stress and conducts triaxial testing on raw coal over various cycle periods.
Yue Jiang, Xingfeng Mao, Dongming Zhang, Xiang Yang   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source