Results 161 to 170 of about 6,560,570 (376)

Breakwater stability with damaged single layer armour units

, 2013
Richard de Rover
openalex   +2 more sources

Arabidopsis γ-H2A.X-INTERACTING PROTEIN participates in DNA damage response and safeguards chromatin stability [PDF]

, 2022
Tianyi Fan, Huijia Kang, Di Wu, Xinyu Zhu, Lin Huang, Jiabing Wu, Yan Zhu   +6 more
openalex   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

DNA Damage-Induced, S-Phase Specific Phosphorylation of Orc6 is Critical for the Maintenance of Genome Stability [PDF]

, 2023
Yo-Chuen Lin, Dazhen Liu, Arindam Chakraborty, Virgilia Macias, Eileen Brister, Jay Sonalkar, Linyuan Shen, Jaba Mitra, Taekjip Ha, Andre Kajdacsy‐Balla, Kannanganattu V. Prasanth, Supriya G. Prasanth   +11 more
openalex   +1 more source

Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

Nature reviews. Molecular cell biology, 2016
Y. Pommier, Yilun Sun, Shar-yin N. Huang, J. Nitiss   +3 more
semanticscholar   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Study on Damage Characteristics and Physical Field Characteristics of Roadway Surrounding Rock Under Multiple Disturbances

Energy Science & Engineering
During the mining process, repetitive stress disturbances induced by mining activities can lead to alterations in the physical properties of coal, potentially resulting in rockburst occurrences within tunnels.
Jiuxin Zhang, Hongyan Qin, Zhenhua Ouyang, Ningbo Zhang, Yiyan Zhang, Yang Liu, Wenshuai Li, Ranran Zhou   +7 more
doaj   +1 more source

Light induces oxidative damage and protein stability in the fungal photoreceptor Vivid

, 2018
Carmen N. Hernández-Candia, Sergio Casas‐Flores, Braulio Gutiérrez–Medina   +2 more
openalex   +2 more sources

Characterizing Excavation Damaged Zone and Stability of Pressurized Lined Rock Caverns for Underground Compressed Air Energy Storage

Rock Mechanics and Rock Engineering, 2013
Hyung-mok Kim, J. Rutqvist, J. Jeong, Byung-Hee Choi, D. Ryu, W. Song   +5 more
semanticscholar   +1 more source