Results 71 to 80 of about 1,086,899 (293)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Technical Note: Alterations in the stone masonry of the Capitol Room of Sevilla City Hall

open access: yesMateriales de Construccion, 2006
The main aim of this work has been to determine the causes of stone loss (small particles and one larger piece) and mortar loss in the coffered vault of the Capitol Room in the City Hall of Seville.
A. Barrios Padura   +2 more
doaj   +1 more source

A shapley value approach to pricing climate risks [PDF]

open access: yes, 2011
This paper prices the risk of climate change by calculating a lower bound for the price of a virtual insurance policy against climate risks associated with the business as usual (BAU) emissions path. In analogy with ordinary insurance pricing, this price
Cooke, Roger M
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Analysis of the Railway Accident-Related Damages in South Korea

open access: yesApplied Sciences, 2020
Railway accidents are critical issues characterized by a large number of injuries and fatalities per accident due to massive public transport systems. This study proposes a new approach for evaluating the damages resulting from railway accidents using ...
Man Sik Park   +3 more
doaj   +1 more source

Experimental Simulations and Tort Reform: Avoidance, Error and Overreaching in Sunstein Et Al.’s ‘Punitive Damages’ [PDF]

open access: yes, 2004
This article addresses tort reform claims made in Cass R. Sunstein, et al.\u27s Punitive Damages: How Juries Decide (2002)and related articles, research that was largely underwritten by the Exxon Corporation. Based upon a series of simulation experiments,
Vidmar, Neil
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

SOME ASPECTS OF HYDROLOGICAL RISK MANIFESTATION IN JIJIA BASIN [PDF]

open access: yesAerul şi Apa: Componente ale Mediului, 2012
Jijia river basin surface geographically fits in Moldavian Plateau, Plain of Moldavia subunit. Being lowered by 200 to 300 m compared to adjacent subunits, it appears as a depression with altitudes between 270-300 m.Through its position in the extra ...
D. BURUIANĂ   +3 more
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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