Results 91 to 100 of about 413,529 (298)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Producer Protection Legislation and Termination Damages in the Presence of Contracting Frictions [PDF]

open access: yes
This study models producer protection legislation that would grant growers the right to claim damages (PPLD) if their contracts are prematurely terminated.
Wu, Steven Y.
core  

Breach of Good Faith in Performance of the Franchise Contract: Punitive Damages and Damages for Intangibles [PDF]

open access: yes, 2004
This paper explores case law concerning breach of good faith in the franchise contract. Given the relational nature of the franchise contract, the good faith term forbids the franchisor from exploiting the franchisee’s classic vulnerability.
O'Byrne, Shannon
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Duty of Damaged Person in Mitigation of Damages in Iranian, French and Common Law [PDF]

open access: yes
In accordance with the rule adopted in the law, any person damage another (physical or psychological damage), the damages must be compensated by injuring person.
مهدوی, عبدالله   +3 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The impact of climate change on global tropical storm damages [PDF]

open access: yes
This paper constructs an integrated assessment model of tropical cyclones in order to quantify the impact that climate change may have on tropical cyclone damages in countries around the world.
Emanuel, Kerry   +2 more
core  

Structural Response of a Two-Side-Supported Square Slab Under Varying Blast Positions from Center to Free Edge and Beyond in a Touch-Off Explosion Scenario

open access: yesBuildings
A touch-off explosion on concrete slabs is considered one of the simplest yet most destructive forms of adversarial loading on building elements. It causes far greater damage than explosions occurring at a distance.
S. M. Anas   +3 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

REMEDIES FOR DAMAGE TO PROPERTY: MONEY DAMAGES OR RESTITUTION IN NATURA? [PDF]

open access: yes
In spite of the great volume of law and economics research carried out in the field of tort law, there exists a gap in the literature concerning the effects of different tort remedies, namely money damages and restitution in natura.
Eleni Zervogianni
core  

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