Results 101 to 110 of about 1,099,010 (309)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
BuildingsA touch-off explosion on concrete slabs is considered one of the simplest yet most destructive forms of adversarial loading on building elements. It causes far greater damage than explosions occurring at a distance.
S. M. Anas +3 more
doaj +1 more source
Using the Statistical Indicators for the General Insurances Activity [PDF]
Theoretical and Applied Economics, 2007 The statistics of the general insurances activity is largely used in the actuarial calculations. The actuarial analysis are achieved exclusively on the basis of primary and derived indicators, which are drawn up by various statistical methods.
Ion Partachi, Constantin Anghelache
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Compensating Market Value Losses: Rethinking the Theory of Damages in a Market Economy [PDF]
, 2011 The BP Deepwater Horizon spill and the Toyota car recalls have highlighted an important legal anomaly that has been overlooked by scholars — judicial inconsistency and confusion in ruling whether to compensate for the loss in market value of wrongfully ...
Schwarcz, Steven L.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A comparison of two alternative methods for determining loss of future earnings following personal injuryí [PDF]
The law provides that any person injured through the fault of another can claim monetary compensation in the form of damages. Restitutio in integrum defines the objective and measure of damages.
Helen Robinson +3 more
core
Damages for Wrongful Death in Alaska [PDF]
, 1988 I den här rapporten presenteras den forskning om ledarskap inom offentliga sektorn som bedrivs vid Linköpings universitet. Kartläggningen är indelad i fem olika teman: Chefers arbete och förutsättningar Ledarskap och lärande Genus och jämställdhet ...
Ingraham, Millard F.
core +1 more source