After the damages directive ::policy and practice in the EU member states and the United Kingdom /
, 2022 After the damages directive in a comparative and interdisciplinary approach provides a comprehensive study of the implementation of the damages directive in all member states of the European Union and the United Kingdom. Designed to deter anticompetitive
Nazzini, Renato, +2 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Compensatory Collective Redress: Will It Be Part of Private Enforcement ofCompetition Law in CEE Countries? [PDF]
Yearbook of Antitrust and Regulatory Studies, 2017 The article aims to compare and evaluate solutions with regard to compensatory collective redress existing in CEE countries. The author will attempt to illuminate obstacles and challenges to using collective redress as an avenue for
Anna Piszcz
doaj +1 more source
International Competition Law: Antitrust Damages Directive Feb 2016 [PDF]
, 2017 This article builds on previous works examining whether private enforcement should be prioritised over public enforcement for breaches of competition law within the EC.
Flaherty, Ruth
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Extending the Principle of Economic Continuity to Private Enforcement of Competition Law. What Lies Ahead for Corporate Restructuring and Civil Damages Proceedings after Skanska?Case Comment to the Judgement of the Court of Justice of 14 March 2019 Skanska Industrial Solutions and others (Case C-724/17 [PDF]
Yearbook of Antitrust and Regulatory Studies, 2019 In the tradition of civil law Member States, civil liability issues are linked to the legal entity that caused a damage, with the exception of lifting the corporate veil.
Vasiliki Fasoula
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The Directive 2014/104/UE on Antitrust Damages Actions: A critical review
Ars Iuris Salmanticensis, 2016 In November 2014, the Directive on antitrust damages actions became law in the EU.This Directive constitutes, undoubtedly, a major step forward in strengthening private enforcement. Indeed, it attempts to facilitate antitrust damages claims and to ensure
Vanessa JIMÉNEZ SERRANÍA
doaj
DNA damage, homology-directed repair and DNA methylation
PLoS Genetics, 2005 To explore the link between DNA damage and gene silencing, we induced a DNA double-strand break in the genome of Hela or mouse embryonic stem (ES) cells using I-SceI restriction endonuclease. The I-SceI site lies within one copy of two inactivated tandem repeated green fluorescent protein (GFP) genes (DR-GFP).
Cuozzo C +13 more
openaire +8 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source