Results 41 to 50 of about 358,508 (301)

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Hydrodynamic Simulation of Flood Due to Hypothetical Momentary Mosul Dam Failure

Tikrit Journal of Engineering Sciences, 2020
Flood wave simulation due to hypothetical momentary failure of Mosul Dam was carried out by applying the (IBER) hydrodynamic model for the dam storage scenarios (300, 310, 320, 330 and 335) meter above sea level after testing the validity and calibration
Thair M. Al-Taiee, Mustafa S. Mustafa
doaj  

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Persistent Mono‐Oxo Bonding with Protactinium(V) Revealed in Highly Acidic Chloride Solutions

Angewandte Chemie, EarlyView.
Protactinium(V) defies expectations. Its elusive mono‐oxo bond was revealed through a combination of extended X‐ray absorption fine structure (EXAFS) and X‐ray absorption near‐edge structure (XANES) analyses, as well as quantum chemical calculations. This bond persists even in 12 M HCl.
Melody Maloubier, Tamara Shaaban, Florent Réal, Claire Le Naour, Hanna Oher, Titouan Aubert, Pier Lorenzo Solari, Bruno Siberchicot, Rémi Maurice, Valérie Vallet   +9 more
wiley   +2 more sources

Effects of maternal subnutrition during early pregnancy on cow hematological profiles and offspring physiology and vitality in two beef breeds [PDF]

, 2019
This experiment evaluated the effects of subnutrition during early gestation on hematology in cows (Bos Taurus) and on hematological, metabolic, endocrine, and vitality parameters in their calves.
Almaguer C., Civelek T., Fay R. A., García‐Belenguer S., Krimer P. M., Lozano M., Schafer S., Schultz R. D., Tchernia G., Tennant B.   +9 more
core   +2 more sources

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Maturity effects in concrete dams [PDF]

, 2004
Model equations for determining the coupled heat, moisture and maturity changes within a concrete block are introduced and briefly examined. Preliminary results are obtained for the heat exchange between concrete slabs in contact driven by maturity ...
Ballim, Y, Fowkes, ND, Makinde, OD, Mambili Mamboundou, H, Patini, A   +4 more
core  

Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques

Advanced Science, EarlyView.
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang, Ying Hu, Yang Teng, Jiwei Qi, Yangzhen Ciren, Lin Zhang, Qiao Du, Wencai Xu, Liang Zhou, Zhenxin Fan, Jinchuan Xing, Ming Li, Jing Li   +12 more
wiley   +1 more source

Quelques considérations sur l'Art Rupestre Schématique d'Andalousie

Zephyrus, 2009
Parmi les grandes étapes artistiques parcourues par l'humanité au cours de la préhistoire, l'art rupestre schématique de la péninsule ibérique occupe une place de premier plan, non seulement par sa grande extensión géographique, mais aussi par les ...
Lya DAMS, Marcel DAMS
doaj  

A Hybrid Particle/Finite Element Model with Surface Roughness for Stone Masonry Analysis

Applied Mechanics, 2022
Circular and spherical particle models are a class of discrete elements (DEM) that have been increasingly applied to fracture studies of quasi-brittle materials, such as rock and concrete, due to their proven ability to simulate fracture processes ...
Nuno Monteiro Azevedo, José V. Lemos
doaj   +1 more source