Results 41 to 50 of about 68,065 (265)
Applied MechanicsRigid particle models (PMs) that explicitly consider the influence of the aggregate structure and its physical interaction mechanisms have been used to predict cracking phenomena in concrete.
Nuno Monteiro Azevedo +2 more
doaj +1 more source
Advanced Science, EarlyView.Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang +6 more
wiley +1 more source
Comparison Study of Two Methods Used to Estimate Surface Runoff Hydrograph for Small Basins
Journal of Engineering and Sustainable Development, 2014 In this study Rainstorm hydrograph peak discharge and unit-hydrograph peak discharge in small basins were calculated and evaluated using various methods for peak discharge assessment applying 6-hour storm rainfall duration. Rainfall-runoff models: HEC-
Abdulwahab Mohammad Younis +2 more
doaj
Safety Assessment of Concrete Gravity Dams: Hydromechanical Coupling and Fracture Propagation
GeosciencesFor the safety assessment of concrete dam–foundation systems, this study used an explicit time-stepping small-displacement algorithm, which simulates the hydromechanical interaction and considers the discrete representation of the foundation ...
Maria Luísa Braga Farinha +2 more
doaj +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Altre Modernità, 2011 My paper analyzes Vittorio Alifieri’s tragedy Saul. The author writes the tragedy after reading the Bible, and particularly Samuel’s first book. Alfieri is enthusiastic about the biblical text, thanks to its “sublime” theme and style, very useful for ...
Paola Trivero
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Advanced Science, EarlyView.A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong +17 more
wiley +1 more source
Tikrit Journal of Engineering SciencesSince Makhol dam is planned to be constructed on Tigris River to the north of Baiji discharge measurement station, it is essential to study the nature of inflow into this reservoir.
Aaisha Mohand Yahya +2 more
doaj +1 more source
Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
Advanced Science, EarlyView.How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source
Advanced Science, EarlyView.The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English +9 more
wiley +1 more source