Results 71 to 80 of about 359,568 (270)

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong   +5 more
wiley   +1 more source

Effects of Geometry, Joint Properties, and Deterioration Scenarios on the Hydromechanical Response of Gravity Dams

open access: yesApplied Mechanics
An explicit coupled two-dimensional (2D) hydromechanical model (HMM) that can simulate discontinuous features in the foundation, as well as the effects of grout curtains and drainage systems, is employed to evaluate the influence of key parameters such ...
Maria Luísa Braga Farinha   +2 more
doaj   +1 more source

Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1‐mediated P53 ubiquitination

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Based on a dermis fibroblast Gorab knockout mouse model, this study revealed that Gorab deficiency promotes skin aging by influencing RCHY1, causing a decrease in P53 ubiquitination, damaging the activity of HDAC2, further resulting in the accumulation of aging‐related proteins (P53, P21, P16) and a reduction in extracellular matrix (ECM) components ...
Yanhong Li   +7 more
wiley   +1 more source

Prediction of Daily Temperature Patterns in Iraq Using Deep Learning Models

open access: yesDiyala Journal of Engineering Sciences
The current study highlights the importance of accurate temperature prediction in Iraq, a country facing economic challenges due to its hot, arid climate and increasing climate change effects.
Mustafa S Mustafa, Basma A.M. Al-Jawadi
doaj   +1 more source

Impact of Euphrates Water Levels on the Hydraulic Properties and Water Quality Parameter in Anbar Province, Iraq [PDF]

open access: yesمجلة جامعة النجاح للأبحاث العلوم الطبيعية
Concentrating on the Haditha Dam reservoir in Anbar Province, Iraq, this study examines the connection between water quality parameters and changes in the Euphrates River's water level.
Sari Aymen Alrawi   +2 more
doaj   +1 more source

Piped water cooling of concrete dams [PDF]

open access: yes, 2004
Piped water is used to remove hydration heat from concrete dams during construction. By examining simple models we obtain an estimate for the temperature rise along the pipe network and within the concrete.
Ballim, Y.   +5 more
core  

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

open access: yesAdvanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq   +5 more
wiley   +1 more source

Trend Analysis of Hydrological Drought for Selected Rivers in Iraq

open access: yesTikrit Journal of Engineering Sciences, 2020
The surface water in study area supports a range of uses such as water supply, irrigation and hydropower generation. Therefore, the assessment and analysis of the hydrological drought are important in the planning and management of the water resources ...
Ihsan F. Hasan, Younis N. Saeed
doaj  

Residual capability of alkali binding by hydrated pozzolanic cements in long-service concrete structures [PDF]

open access: yes, 2018
An experimental procedure was developed and applied to cement pastes made with two different pozzolanic cements (CEM IV/B (P) and CEM IV/B (V)) in order to ascertain the existence of a residual capability of alkali binding by long-term hydrated ...
Antonio Evangelista Paolini, And   +2 more
core   +2 more sources

Hierarchical Complementary Enhanced Autoencoder Integrating Spatio‐Temporal Interaction Feature for Soft Sensor

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT To address the issues of neglecting the spatiotemporal correlations among process variables, low‐level features are vulnerable to noise interference, and the gradual loss of key information layer by layer during deep network training in traditional stacked autoencoder‐based soft‐sensor models, this paper proposes a hierarchical complementary ...
Xiaoping Guo, Jinghong Guo, Yuan Li
wiley   +1 more source

Home - About - Disclaimer - Privacy