Results 51 to 60 of about 16,122 (287)

A correlative model to predict in vivo AUC for nanosystem drug delivery with release rate-limited absorption [PDF]

open access: yes, 2012
Purpose. Drug release from nanosystems at the sites of either absorption or effect biophase is a major determinant of its biological action. Thus, in vitro drug release is of paramount importance in gaining insight for the systems performance in vivo ...
Adibkia, Khosro   +6 more
core   +3 more sources

Danazol increases T regulatory cells in patients with aplastic anemia

open access: yesHematology, 2018
Objectives: Danazol is an attenuated androgen and is used in the treatment of aplastic anemia (AA) in resource constraint settings. We chose to study the role of CD4+ CD25high CD127low FoxP3+ T regulatory cells (T-regs) in the pathophysiology of AA and ...
H. Khurana   +9 more
semanticscholar   +1 more source

Hereditary angioedema may not be the only cause of abdominal pain in patients with hereditary angioedema!

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Abdominal pain is one of the basic clinical presentations of the hereditary angioedema and danazol is a common medicine which has been used for long years in patients with hereditary angioedema.
Ozgur Kartal   +7 more
doaj   +1 more source

Maintenance therapy with a combination of azacitidine, danazol, and thalidomide after intensive chemotherapy in patients with acute myeloid leukemia

open access: yesHematology, 2023
Objective This study aimed to evaluate the efficacy of azacitidine (AZA) combined with danazol (DNZ) and thalidomide (THD) maintenance therapy after intensive chemotherapy (IC) in patients with acute myeloid leukemia (AML).Methods we retrospectively ...
Fang Zheng   +5 more
doaj   +1 more source

Danazol Induced Thrombocytopenia.

open access: yesThe Tohoku Journal of Experimental Medicine, 1997
A 34-year-old woman with a left ovarian cyst (clinically diagnosed as endometrial cyst) was treated with 400 mg of danazol per day. On the next day, after a total dose of only 600 mg of danazol, gingival bleeding and purpura occurred. Her laboratory findings were as follows: platelet count 1000/ mm3 hematocrit 39%, WBC 7300/mm3 and RBC 466 x 10(4)/mm3.
Hiroshi Hoshiai   +5 more
openaire   +4 more sources

Use of Cyclosporine A and danazol in treatment of aplastic anemia: A real-world data from a teaching hospital in South India

open access: yesAsian Journal of Medical Sciences, 2022
Background: Due to financial constraints, there are limited treatment options for Aplastic anemia (AA) in developing countries. Aims and Objectives: In the present observational retrospective study, utility of Cyclosporine A (CsA) along with Danazol ...
Girish Kamat   +6 more
doaj   +1 more source

Idiopathic Thrombocytopenic Purpura Misdiagnosed as Hereditary Angioedema [PDF]

open access: yes, 2015
Hereditary angioedema is a rare, but potentially life-threatening genetic disorder that results from an autosomal dominant trait. It is characterized by acute, recurrent attacks of severe local edema, most commonly affecting the skin and mucosa. Swelling
Andersen, Michelle Fog, Bygum, Anette
core   +4 more sources

Mixed Autoimmune Hemolytic Anemia: A Systematic Review of Epidemiology, Clinical Characteristics, Therapies, and Outcomes

open access: yesAmerican Journal of Hematology, EarlyView.
Mixed autoimmune hemolytic anemia (AIHA) is a rare condition characterized by the presence of both warm and cold autoantibodies, often leading to severe, treatment‐resistant hemolysis. In this systematic review of 81 patients across 35 studies, the median age was 45 years with a notable female predominance.
Jeremy W. Jacobs   +12 more
wiley   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

open access: yesDrug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis   +2 more
wiley   +1 more source

Abdominal-pelvic pain in female patients with endometriosis - a review of the literature [PDF]

open access: yes, 2018
Abdominal-pelvic pain is the dominant symptom in endometriosis, one of the most common pathologies that affect women, being also a multifactorial disorder.
Andronache, Liliana Florina   +8 more
core   +1 more source

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