Results 31 to 40 of about 6,348 (189)

Danazol therapy for cyclic thrombocytopenia

, 1991
Cyclic thrombocytopenia is a rare disease characterized by cyclic oscillations of platelet counts from very low to normal or higher. Severe hemorrhage may occur during the thrombocytopenic phase.
Ahn, Yeon S, Rocha, Rafael, Mylvaganam, Ravindra, Harrington, William J, Horstman, Lawrence   +4 more
core   +1 more source

Immune modulation by danazol in autoimmune thrombocytopenia

, 1987
Danazol, an attenuated androgen, has recently been introduced into the treatment of autoimmune thrombocytopenia. We studied its effects on T helper/inducer (Thi) and T suppressor/cytotoxic (Tsc) lymphocytes in these patients.
Kim, Chae I, Ahn, Yeon S, Mylvaganam, Ravindra, Harrington, William J   +3 more
core   +1 more source

Danazol Therapy in Hereditary Angioedema [PDF]

, 1980
Herditary angioedema (HAE) is an autosomal dominantly inherited condition in which a deficiency of the inhibitor (C1lnh) of the activated first component of complement is associated with recurrent episodes of edema of the skin, gastrointestinal tract ...
Yott, J. B., Yanari, Sam S., Sweet, Lawrence C., Jackson, Charles E.   +3 more
core   +1 more source

Real‐World Safety and Effectiveness of Icatibant in Patients With Hereditary Angioedema (HAE): Post‐Marketing Surveillance in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Hereditary angioedema (HAE) is a rare, autosomal dominant, life‐threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1‐inhibitor (C1‐INH) plasma protein are associated with HAE‐C1INH.
Kumiko Hosono, Miyako Hoshino
wiley   +1 more source

Danazol’s use for menstrual suppression in transgender individuals: A retrospective multi-site cohort study

Women's Health
Background: Danazol is a synthetic progestin with androgenic effects that is approved by the Food and Drug Administration for treatment of endometriosis, benign fibrocystic breast disease, and hereditary angioedema. In recent years, increasing numbers of
Ava Scatoni, Zaine Roberts, Elizabeth R Boskey, Steven Staffa, Rosemary Claire Roden, Emile Redwood, Frances Grimstad   +6 more
doaj   +1 more source

Hereditary angioedema may not be the only cause of abdominal pain in patients with hereditary angioedema!

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Abdominal pain is one of the basic clinical presentations of the hereditary angioedema and danazol is a common medicine which has been used for long years in patients with hereditary angioedema.
Ozgur Kartal, Sevket Arslan, Mustafa Gulec, Ahmet Zafer Caliskaner, Abdullah Baysan, Nail Ersoz, Ugur Musabak, Osman Sener   +7 more
doaj   +1 more source

Survival outcomes and treatment patterns in myelofibrosis in the JAK inhibitor era

British Journal of Haematology, EarlyView.
Summary Data on real‐world survival and treatment patterns in large, unselected myelofibrosis (MF) cohorts remain limited. We analysed 1649 patients with MF diagnosed from 2010 onwards and included in the Spanish Myelofibrosis Registry across 64 centres. Janus kinase (JAK) inhibitors were administered to approximately half of the patients.
Juan‐Carlos Hernández‐Boluda, Eduardo Arellano‐Rodrigo, Manuel Pérez‐Encinas, José‐María Raya, María‐Teresa Gómez‐Casares, Francisca Ferrer‐Marín, Alberto Hernández‐Sánchez, María‐Laura Fox, Anna Angona, Beatriz Cuevas, María‐Isabel Mata‐Vázquez, Rosa Ayala, Natalia de las Heras, Elvira Mora, Valentín García‐Gutiérrez, Alicia Senín, Jasson Villarreal, Blanca Xicoy, Raúl Pérez‐López, María García‐Fortes, Sonia González de Villambrosia, Elena Magro, María‐José Ramírez, Paula Gómez, Angel Ramírez‐Payer, Clara Martínez‐Valverde, Lucía Pérez‐Lamas, Carmen García‐Hernández, Mercedes Gasior, Luis‐Miguel Juárez‐Salcedo, Francisco Ibáñez, María‐Luisa Antelo, Lucía Guerrero, Alberto Alvarez‐Larrán, Arturo Pereira, on behalf of the Spanish MPN Group (GEMFIN)   +35 more
wiley   +1 more source

Adjuvant administration of danazol contributed to the maintenance of platelet counts in two dogs with splenectomy-unresponsive immune-mediated thrombocytopenia

Open Veterinary Journal
Background: Maintaining platelet (PLT) counts with lower doses of corticosteroid is an important clinical goal in the treatment of immune-mediated thrombocytopenia (IMT) in dogs.
Keiichi Furusawa, Yuji Fujii, Tetsuya Shimoda, Yui Kobatake, Satoshi Takashima, Naohito Nishii   +5 more
doaj   +1 more source

Janus kinase inhibitors after ruxolitinib failure in myelofibrosis: A systematic review and pooled analysis of phase 3 efficacy and integrated safety across clinical trials and real‐world evidence

British Journal of Haematology, EarlyView.
Summary Ruxolitinib remains first‐line standard of care for symptomatic myelofibrosis, but resistance/intolerance develops in most patients. Three Janus kinase inhibitors (JAKis) have entered the post‐ruxolitinib space via distinct pivotal trials. We systematically searched prospective trials evaluating JAKi in refractory adults with myelofibrosis ...
Andrea Duminuco, Patrick Harrington, Elena Torre, Hillary Catellani, Novella Pugliese, Matteo Pacilli, Annalisa Santisi, Arianna Sbriglione, Giuseppe A. Palumbo   +8 more
wiley   +1 more source

Danazol for pelvic pain associated with endometriosis

, 2010
Background Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease the deposits of ectopic ...
Singla, A, Prentice, A, Farquhar, Cynthia, Selak, Vanessa   +3 more
core   +1 more source