Results 21 to 30 of about 10,610 (205)

An anesthetic experience of hereditary angioedema type I patient undertook total laparoscopic hysterectomy - A case report - [PDF]

open access: yesAnesthesia and Pain Medicine, 2022
Background Hereditary angioedema (HAE) is an autosomal dominant disorder. The characteristic of HAE is recurrent angioedema episodes due to low C1 esterase inhibitor (C1-INH) level.
Yun-Sic Bang, Jaeho Cho, Chunghyun Park
doaj   +1 more source

Danazol mediates collateral sensitivity via STAT3/Myc related pathway in multidrug-resistant cancer cells

open access: yesScientific Reports, 2019
Multidrug resistance presents an obstacle in cancer treatment. Among numerous combative strategies, collateral sensitivity (CS) drugs have opened a new avenue to defeat cancer by exploiting selective toxicity against multidrug-resistant (MDR) cancer.
Ying-Tzu Chang   +6 more
doaj   +1 more source

Combined therapy with danazol, pegilated interferon, and ribavirin improves thrombocytopenia and liver injury in rats with fibrosis

open access: yesAnnals of Hepatology, 2007
The aim of this study was to investigate the effects of combinations of pegilated–interferon (PEG–IFN), ribavirin, and danazol on thrombocytopenia and liver injury in rats with fibrosis.
Guillermo Cabrera Álvarez   +7 more
doaj   +1 more source

The Use of Natural Agents to Counteract Telomere Shortening: Effects of a Multi-Component Extract of Astragalus mongholicus Bunge and Danazol

open access: yesBiomedicines, 2020
A link between telomere shortening and oxidative stress was found in aging people and patients with cancer or inflammatory diseases. Extracts of Astragalus spp. are known to stimulate telomerase activity, thereby compensating telomere shortening.
Isabelle Guinobert   +12 more
doaj   +1 more source

Comparative effects of coconut water and N-Acetyl cysteine on the hypothalamo-pituitary-gonadal axis of male rats [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2017
Coconut water (CW) contains cysteine, an amino acid which influences glutathione metabolism and promotes reproductive functions. The effects of CW and N-acetyl cysteine (NAC) were compared on the hypothalamo-pituitary-gonadal-axis of danazol-(a GnRH ...
Olufadekemi Tolulope Kunle-Alabi   +4 more
doaj   +1 more source

Evaluating the Efficacy of Levonorgestrel Intrauterine System and Danazol for Relief of Postoperative Pain in Endometriosis [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Endometriosis is an oestrogen-dependent disorder, manifests during reproductive years and is associated with pain and infertility. There is considerable debate about the effectiveness of various interventions for pain relief.
Ashima Taneja   +5 more
doaj   +1 more source

TELO-SCOPE study: a randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosis

open access: yesBMJ Open Respiratory Research, 2021
Introduction Recent discoveries have identified shortened telomeres and related mutations in people with pulmonary fibrosis (PF). There is evidence to suggest that androgens, including danazol, may be effective in lengthening telomeres in peripheral ...
Tamera J Corte   +19 more
doaj   +1 more source

Acute lower limb ischemia due to thrombo-embolic arterial occlusions in two previously healthy men with markedly elevated Lp(a) [PDF]

open access: yes, 2006
Lipoprotein (a) (Lp(a)) is a well-documented risk factor for atherosclerotic cardiovascular disease. Its role in acute thrombo-embolic occlusions of peripheral arteries is not known.
Federico Tatò   +6 more
core   +4 more sources

Evaluation of Danazol, Cyclosporine, and Prednisolone as Single Agent or in Combination for Paroxysmal Nocturnal Hemoglobinuria

open access: yesTurkish Journal of Hematology, 2013
OBJECTIVE: The responses of 32 patients with paroxysmal nocturnal hemoglobinuria (PNH) were assessed after the patients were put on various combinations of danazol, prednisolone, and cyclosporine.
Kanjaksha Ghosh   +3 more
doaj   +1 more source

A Randomized Controlled Intervention Trial with Danazol to Improve Telomeric and Fertility Parameters in Women with Diminished Ovarian Reserve: A Pilot Study

open access: yesWomen's Health Reports, 2023
Background: Most women who are treated at in vitro fertilization (IVF) clinics have trouble conceiving due to ovarian failure (OF), which seems to be associated to short telomeres and reduced or absent telomerase activity in their granulosa cells. Indeed,
Isabel C?rdova-Oriz   +9 more
doaj   +1 more source

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