Results 21 to 30 of about 6,348 (189)

An anesthetic experience of hereditary angioedema type I patient undertook total laparoscopic hysterectomy - A case report - [PDF]

Anesthesia and Pain Medicine, 2022
Background Hereditary angioedema (HAE) is an autosomal dominant disorder. The characteristic of HAE is recurrent angioedema episodes due to low C1 esterase inhibitor (C1-INH) level.
Yun-Sic Bang, Jaeho Cho, Chunghyun Park
doaj   +1 more source

The German ONKOPEDIA Guideline for Myelofibrosis in 2025-Recommendations of an MPN Expert Panel of the German Society for Hematology and Oncology (DGHO). [PDF]

Int J Cancer
ABSTRACT The recently published ONKOPEDIA guideline on myelofibrosis, issued under the auspices of the German Society of Hematology and Oncology (DGHO), provides an updated, evidence‐based framework for the diagnosis and management of this rare, chronic myeloproliferative neoplasm.
Griesshammer M, Al-Ali HK, Baerlocher GM, Döhner K, Koschmieder S, Kröger N, Petrides PE, Wolf D, Heidel FH.   +8 more
europepmc   +2 more sources

Comparative effects of coconut water and N-Acetyl cysteine on the hypothalamo-pituitary-gonadal axis of male rats [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2017
Coconut water (CW) contains cysteine, an amino acid which influences glutathione metabolism and promotes reproductive functions. The effects of CW and N-acetyl cysteine (NAC) were compared on the hypothalamo-pituitary-gonadal-axis of danazol-(a GnRH ...
Olufadekemi Tolulope Kunle-Alabi, Opeyemi Oreofe Akindele, Maximillian I. Odoh, Bright Onome Oghenetega, Yinusa Raji   +4 more
doaj   +1 more source

The Use of Natural Agents to Counteract Telomere Shortening: Effects of a Multi-Component Extract of Astragalus mongholicus Bunge and Danazol

Biomedicines, 2020
A link between telomere shortening and oxidative stress was found in aging people and patients with cancer or inflammatory diseases. Extracts of Astragalus spp. are known to stimulate telomerase activity, thereby compensating telomere shortening.
Isabelle Guinobert, Claude Blondeau, Bruno Colicchio, Noufissa Oudrhiri, Alain Dieterlen, Eric Jeandidier, Georges Deschenes, Valérie Bardot, César Cotte, Isabelle Ripoche, Patrice Carde, Lucile Berthomier, Radhia M’Kacher   +12 more
doaj   +1 more source

TELO-SCOPE study: a randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosis

BMJ Open Respiratory Research, 2021
Introduction Recent discoveries have identified shortened telomeres and related mutations in people with pulmonary fibrosis (PF). There is evidence to suggest that androgens, including danazol, may be effective in lengthening telomeres in peripheral ...
Tamera J Corte, Adam Jaffe, Christopher Grainge, Jeremy Wrobel, Hiran Selvadurai, Stephanie T Yerkovich, Daniel C Chambers, Maxine Tan, Ian Glaspole, Peter Hopkins, Paul N Reynolds, Hilda A Pickett, Nicole S Goh, John A Mackintosh, Maria Pietsch, Viviana Lutzky, Debra Enever, Sandra Bancroft, Simon H Apte, Joanne L Dickinson   +19 more
doaj   +1 more source

A Randomized Controlled Intervention Trial with Danazol to Improve Telomeric and Fertility Parameters in Women with Diminished Ovarian Reserve: A Pilot Study

Women's Health Reports, 2023
Background: Most women who are treated at in vitro fertilization (IVF) clinics have trouble conceiving due to ovarian failure (OF), which seems to be associated to short telomeres and reduced or absent telomerase activity in their granulosa cells. Indeed,
Isabel C?rdova-Oriz, Graciela Kohls, Carlos Iglesias, Alba M. Polonio, Luc?a Chico-Sordo, M?nica Toribio, Marcos Meseguer, Elisa Varela, Antonio Pellicer, Juan A. Garc?a-Velasco   +9 more
doaj   +1 more source

Danazol one Month Treatment of Thrombocytopenia in Chronic Hepatitis C

Medicine Science, 2016
Thrombocytopenia is frequently observed in patients with chronic hepatitis C virus. Moderate and severe thrombocytopenia ( [Med-Science 2016; 5(1.000): 209-21]
Hosam Dawod, Sameh Abdel Monem
doaj   +1 more source

Evaluating the Efficacy of Levonorgestrel Intrauterine System and Danazol for Relief of Postoperative Pain in Endometriosis [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Endometriosis is an oestrogen-dependent disorder, manifests during reproductive years and is associated with pain and infertility. There is considerable debate about the effectiveness of various interventions for pain relief.
Ashima Taneja, Satinder Kaur, R.K. Soni, Bhanupriya, Jaspreet Kaur, Laveen Singla   +5 more
doaj   +1 more source

Bleeding Stomal Varices and Vascular Interventional Radiology Management: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Stomal varices are a rare but life‐threatening complication of portal hypertension. While multiple approaches are used to treat these varices, clinicians often face significant diagnostic and therapeutic challenges. A 55‐year‐old woman with a history of cirrhosis and low rectal cancer presented with massive stomal variceal bleeding requiring ...
Bolourinejad P, Tavallaeinejad P, Jafarpisheh MS.   +2 more
europepmc   +2 more sources

A multicriteria decision analysis (MCDA) applied to three long-term prophylactic treatments for hereditary angioedema in Spain

Global & Regional Health Technology Assessment, 2022
Introduction: Hereditary angioedema (HAE) is a rare genetic disease that impairs quality of life and could be life-threatening. The aim of this study was to apply a multicriteria decision analysis to assess the value of three long-term prophylactic (LTP)
Néboa Zozaya, Teresa Caballero, Teresa González-Quevedo, Pedro Gamboa Setien, M. Ángeles González, Ramón Jódar, José Luis Poveda-Andrés, Encarna Guillén-Navarro, Agustín Rivero Cuadrado, Álvaro Hidalgo-Vega   +9 more
doaj   +1 more source