Results 51 to 60 of about 6,348 (189)

Danazol and limb-threatening arterial thrombosis: Two case reports [PDF]

open access: yes, 2001
Danazol is a synthetic androgenic steroid used clinically for the treatment of a wide variety of disorders. Although there is no extensive evidence that androgens are thrombogenic in humans, there are case reports of cerebral, coronary, and peripheral ...
Liu, Jean Y.   +2 more
core   +1 more source

Splenic peliosis with spontaneous splenic rupture in a patient with immune thrombocytopenia treated with danazol

open access: yesHaematologica, 1998
We present a 79-year-old man diagnosed with immune thrombocytopenia (ITP), treated with danazol, who died as a result of a spontaneously ruptured spleen. The histopathological diagnosis was splenic peliosis.
F Javier Penalver   +5 more
doaj  

Hepatocellular Carcinoma in a Noncirrhotic Liver after Long-Term Use of Danazol for Hereditary Angioedema

open access: yesCase Reports in Oncology, 2014
We report a 57-year-old male who was treated with high-dose danazol for hereditary angioedema for more than 30 years; he developed hepatocellular carcinoma in the absence of cirrhosis.
Soraya Rahal   +5 more
doaj   +1 more source

Sustained Effectiveness of Lanadelumab in Preventing Hereditary Angioedema Attacks: The ENABLE Study

open access: yesClinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT Background Lanadelumab has been approved for hereditary angioedema (HAE) long‐term prophylaxis since 2018. The Phase 4, prospective ENABLE Study (NCT04130191) evaluated the long‐term effectiveness and safety of lanadelumab in clinical practice across Europe and the Middle East.
Andrea Zanichelli   +15 more
wiley   +1 more source

Berotralstat Tolerability and Effectiveness in Hereditary Angioedema: Berolife Study Results

open access: yesClinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT Background Berotralstat is a first‐line once‐daily oral prophylactic treatment for hereditary angioedema (HAE). Berolife was designed to evaluate the tolerability and effectiveness of berotralstat in real‐world conditions. Methods Berolife is an open‐label, multicenter, observational study conducted in France from September 2021 to January ...
Delphine Gobert   +26 more
wiley   +1 more source

The Beneficial Interaction Between Enalapril and Danazol in Normal Rat

open access: yes, 2002
Danazol, a weekly androgenic, heterocyclic compound with anabolic properties, is used primarily in the treatment of endometriosis and other gynecological complaints.
Al-Majed A.   +5 more
core   +1 more source

Trombocitopenia asociada a infección con virus de inmunodeficiencia humana tipo 1 (HIV-1): Tratamiento con danazol

open access: yesRevista Médica Herediana, 1996
Objetivo: Evaluar la eficacia del danazol para el tratamiento de la trombocitopenia asociada con el virus de la inmunodeficiencia humana tipo 1 (HIV-1). Pacientes y Métodos: Estudio retrospectivo, diseño serie de casos.
Dushyantha T Jayaweera   +3 more
doaj  

Assessment of potential drug-drug interactions in patients with hereditary angioedema from the ITACA cohort: simulations from a real-life dataset considering danazol versus berotralstat

open access: yesFrontiers in Pharmacology
BackgroundDanazol is regularly used as a prophylactic treatment in patients with Hereditary angioedema due to C1-inhibitor deficiency (HAE-C1INH). However, this drug is characterized by a risk of drug-drug interactions (DDIs).
Andrea Zanichelli   +26 more
doaj   +1 more source

Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura

open access: yesCanadian Respiratory Journal, 2004
The case of a patient that developed pulmonary fibrosis two months after initiation of danazol for treatment of idiopathic thrombocytopenic purpura is described.
Smita Pakhale   +3 more
doaj   +1 more source

Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions – A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aim Human T‐Lymphotropic virus type 1 (HTLV‐1) infection can lead to HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a debilitating chronic neurological disease characterized by progressive lower limb spasticity and autonomic dysfunction.
Meygol Mirzaei Rezaei   +11 more
wiley   +1 more source

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