Results 71 to 80 of about 16,122 (287)
Enhanced bioavailability of danazol nanosuspensions by wet milling and high-pressure homogenization
Introduction: The majority of drugs obtained through synthesis and development show poor aqueous solubility and dissolution velocity, resulting in reduced bioavailability of drugs. Most of these problems arise from formulation-related performance issues,
Naveen Kanthamneni+4 more
semanticscholar +1 more source
Avatrombopag for the Treatment of Immune Thrombocytopenia
ABSTRACT Avatrombopag, a second‐generation thrombopoietin receptor agonist (TPO‐RA), represents a significant advancement in the treatment of chronic immune thrombocytopenic purpura (cITP) and a potential therapeutic option for other thrombocytopenic disorders.
Caterina Labanca+11 more
wiley +1 more source
The aim of this study was to investigate the effects of combinations of pegilated–interferon (PEG–IFN), ribavirin, and danazol on thrombocytopenia and liver injury in rats with fibrosis.
Guillermo Cabrera Álvarez+7 more
doaj
The effect of long-term danazol treatment on haematological parameters in hereditary angioedema
BackgroundThe 17-alpha-alkylated derivatives of testosterone are often used for the prevention of oedematous episodes in hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE).
K. V. Kőhalmi+7 more
semanticscholar +1 more source
Endometriosis is diagnosed when tissue which resembles the endometrial lining exists outside the endometrial cavity. Although first described as a pathological entity in the late 1800s, the term “endometriosis” was not introduced until the early 1920s by
Hurt, W. Glenn, Wetheim, Ray A.
core +2 more sources
By systematizing a large body of evidence and propose a cascade relationship between protein homeostasis, endoplasmic reticulum stress, mitochondrial dysfunction, and pro‐fibrotic factor, providing a theoretical basis for ATII cells dysfunction as a possible pathophysiological initiating event for idiopathic pulmonary fibrosis.
Zhaoxiong Dong+6 more
wiley +1 more source
Objetivo: Evaluar la eficacia del danazol para el tratamiento de la trombocitopenia asociada con el virus de la inmunodeficiencia humana tipo 1 (HIV-1). Pacientes y Métodos: Estudio retrospectivo, diseño serie de casos.
Dushyantha T Jayaweera+3 more
doaj
Drugs in the treatment of endometriosis [PDF]
Endometriosis affects approximately 3% of women of reproductive age. The term endometriosis is applied to a condition where actively functioning endometrium is found in ectopic situations other than lining the uterine cavity, such as bladder, ovaries,
Magri Demajo, Josianne
core
Rare presentations of small bowel endometriosis
Abstract Despite endometriosis being a relatively common chronic gynecological condition in women of childbearing age, small bowel endometriosis is rare. Presentations can vary from completely asymptomatic to reported symptoms of abdominal pain, bloating, and diarrhea.
Anthony Sakiris+7 more
wiley +1 more source
Effects of anabolic steroids on acute phase responses in intra-abdominal sepsis
The acute phase response is an important adaptive response to sepsis and injury. As anabolic steroids increase protein synthesis we postulated that these agents might also increase hepatic acute phase protein synthesis.
K. Mealy+4 more
doaj +1 more source