Results 1 to 10 of about 4,130 (205)
Transient autoantibodies to danger signals [PDF]
Frontiers in Immunology, 2023 The Danger Model predicts that there are some molecules that no immune system can ever be fully tolerant of, namely proteins that are only transiently expressed during times of stress, infection, or injury. Among these are the danger/alarm signals themselves.
Polly Matzinger, Matzinger Polly
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Danger signals: Chemotherapy enhancers?
Immunological Reviews, 2017 SummaryEndogenous danger signals are molecules normally present in a given cell compartment that are rapidly released following cell stress and induce immune responses. We and others have shown that dying tumor cells treated with some chemotherapies are able to induce anticancer immune responses, which rely on their release of danger signals such as ...
Thaiz Rivera Vargas, Lionel Apetoh
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Preferred Levels of Auditory Danger Signals
International Journal of Occupational Safety and Ergonomics, 2000 An important issue at the design stage of the auditory danger signal for a safety system is the signal audibility under various conditions of background noise.
Nagórski, A., Żera, J.
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The danger within: endogenous danger signals, atopy and asthma
Clinical & Experimental Allergy, 2009 SummaryIn allergic asthmatics, airway inflammation is triggered by specific (inhalation of allergen such as house dust mite allergen and pollen spores) or non‐specific triggers (such as air pollutants and viral infection). Most of these inhaled particles are immunologically inert.
M A M, Willart, B N, Lambrecht
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Danger Signaling in Atherosclerosis [PDF]
Circulation Research, 2015 All aspects of the pathogenesis of atherosclerosis are critically influenced by the inflammatory response in vascular plaques. Research in the field of innate immunity from the past 2 decades has uncovered many novel mechanisms elucidating how immune cells sense microbes, tissue damage, and metabolic derangements.
Zimmer, Sebastian +2 more
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Danger Signals in the ICU [PDF]
Critical Care Medicine, 2018 Objectives: Sterile and infectious critical illnesses often result in vasoplegic shock and a robust systemic inflammatory response that are similar in presentation. The innate immune system is at the center of the response to both infectious and traumatic insults.
Edward J, Schenck +3 more
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Danger signals in trauma [PDF]
European Journal of Trauma and Emergency Surgery, 2018 This review summarizes a short list of currently discussed trauma-induced danger-associated molecular patterns (DAMP). Due to the bivalent character and often pleiotropic effects of a DAMP, it is difficult to describe its "friend or foe" role in post-traumatic inflammation and regeneration, both systemically as well locally in tissues. DAMP can be used
Relja, Borna +2 more
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Allergy / AllergoOncology: danger signals in allergology and oncology: a European Academy of Allergy and Clinical Immunology (EAACI) position paper [PDF]
, 2022 The immune system interacts with many nominal ‘danger’ signals, endogenous danger-associated (DAMP), exogenous pathogen (PAMP) and allergen (AAMP)-associated molecular patterns.
Bax, Heather J. +9 more
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A Dangerous Signal to Science [PDF]
Science, 2004 W hen you rush, you make mistakes. The recently passed U.S. budget for fiscal year (FY) 2005, finalized in a scurry to complete the congressional lame duck session, did more than just shortchange science. Perhaps worse, it sent a dangerous message that will reverberate throughout the global science and technology enterprise for a long time to come ...
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