Results 11 to 20 of about 26,373 (204)
Population Genomics for Coral Reef Restoration-A Case Study of Staghorn Corals in Micronesia. [PDF]
Evol ApplABSTRACT Staghorn Acropora corals are ecological keystone species in shallow lagoons and back reef habitats throughout the tropics. Their widespread decline coupled with their amenability for asexual propagation propelled them to the forefront of global coral restoration efforts—albeit frequently without much scientific input.
Rios D +6 more
europepmc +2 more sources
Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial-mesenchymal transition and tumor-infiltrating lymphocytes. [PDF]
Mol OncolEpithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Derouane F +16 more
europepmc +2 more sources
Public attitudes and intentions toward engaging in reintroduction of wolves to Japan
Conservation Biology, Volume 37, Issue 6, December 2023., 2023 Abstract Reintroducing apex predators is an important approach in ecosystem restoration; however, it is challenging. Wolves (Canis lupus) were exterminated in Japan around 1900, and since then, there has been a lack of top predators throughout the country.
Ryo Sakurai +3 more
wiley +1 more source
PLAU contributes to the development of cholangiocarcinoma via activating NF‐κB signaling pathway
Cell Biology International, Volume 47, Issue 8, Page 1381-1391, August 2023., 2023 Abstract Cholangiocarcinoma (CCA) is a type of epithelial cancer with poor outcomes and late diagnosis. Accumulating evidence has demonstrated the promoting role of plasminogen activator, urokinase (PLAU) in several tumor types, while its function in CCA is largely unknown.
Mei‐Di Hu +2 more
wiley +1 more source
Molecular Genetics &Genomic Medicine, Volume 11, Issue 5, May 2023., 2023 An automated and manual curation workflow allows us to reclassify 16% (95/601) of the genetic variants identified in a Latin American population with a suspected hereditary cancer syndrome. VUS corresponded to 71% of the reclassified variants; from these, 91% were downgraded to B/LB and only 9% were upgraded to P/LP. Our results contribute to improving
María Carolina Manotas +2 more
wiley +1 more source
Acta Crystallographica Section D, Volume 79, Issue 2, Page 177-187, February 2023., 2023 The crystallographic structure of the DnaB·DciA complex from Vibrio cholerae reveals that the various helicase loaders share the same binding site on the bacterial replicative helicase, albeit with differences in their loading mechanisms.During the initiation step of bacterial genome replication, replicative helicases depend on specialized proteins for
Claire Cargemel +7 more
wiley +1 more source
Disease Markers, Volume 2022, Issue 1, 2022., 2022 By the year 2050, the world’s elderly population may increase exponentially, raising the rate of disease characteristic of this group, such as prostate cancer (PCa) and benign prostatic hyperplasia (BPH). Prostate disorders have a multifactorial etiology, especially age and genetic factors.
Tamara Silva +11 more
wiley +1 more source
Neurobiology of resilience in depression: immune and vascular insights from human and animal studies
European Journal of Neuroscience, Volume 53, Issue 1, Page 183-221, January 2021., 2021 Endocrine, immune and vascular aspects contributing to depression and resilience. Evidence from mouse and human studies highlighted sex‐specific roles of these three different, but associated, systems in major depressive disorder and resilience. Abstract Major depressive disorder (MDD) is a chronic and recurrent psychiatric condition characterized by ...
Katarzyna A. Dudek +5 more
wiley +1 more source
Acta Cirúrgica Brasileira, 2010 PURPOSE: Quantify the levels of oxidative DNA damage of epithelial colon cells comparing segments with and without fecal stream. METHODS: Sixty Wistar rats were subjected to deviation of fecal stream by proximal colostomy and a distal mucosal fistula ...
Carlos Augusto Real Martinez +5 more
doaj +1 more source
Álcool e Câncer Bucal: Considerações sobre os Mecanismos Relacionados
Revista Brasileira de Cancerologia, 2008 O consumo de álcool é um dos fatores de risco para o desenvolvimento do câncer bucal; entretanto, os mecanismos envolvidos no dano gerado pelo álcool são parcialmente compreendidos. Determinadas concentrações de álcool causam aumento da permeabilidade da
Vinícius Coelho Carrard +4 more
doaj +1 more source