Results 11 to 20 of about 4,965 (233)
Hepatitis from dantrolene sodium. [PDF]
Gut, 1979 The clinical course and histological changes in the liver during a presumed adverse reaction to the drug dantrolene sodium are described in four patients. After a typical prodrome one developed a moderately severe hepatitis-like illness. Another also had a prodrome but never became jaundiced.
S P Wilkinson, B Portmann, R Williams
openalex +5 more sources
A Novel Dantrolene Sodium-Loaded Mixed Micelle Containing a Small Amount of Cremophor EL: Characterization, Stability, Safety and Pharmacokinetics [PDF]
Molecules, 2019 Dantrolene sodium (DS) is the only drug specifically used for the treatment of malignant hyperthermia. Nevertheless, its clinical application is significantly restricted due to its aqueous insolubility and the limited formulations available in clinical ...
Wenzhen Jin +8 more
doaj +2 more sources
Mode of action of dantrolene sodium in spasticity [PDF]
Acta Neurologica Scandinavica, 2009 The mode of action of dantrolene sodium was studied in 11 multiple sclerosis patients with spastic paresis of the legs by measurements of changes in electromyographic and mechanomyographic proprioceptive reflex responses and in voluntary power. Dantrolene sodium 0.5 mg per kg body weight given intravenously clearly reduced monosynaptic reflex twitch ...
Jesper Mai, Ejner Pedersen
openalex +3 more sources
A comparison of dantrolene sodium and diazepam in the treatment of spasticity [PDF]
Spinal Cord, 1974 This is a report on the effect of Dantrolene Sodium which the authors have examined on 62 patients in comparison with Diazepam. They found that Dantrolene Sodium is more efficient than Diazepam in the treatment of patients with spasticity. In some cases the combination of the two drugs was found to be more effective than either drug alone.
Alvin Glass, Adrienne Hannah
openalex +4 more sources
Talanta OpenThis work provides a cost-effective, environmentally benign, rapidly prepared, highly fluorescent carbon dots (CDs) using renewable antioxidants-rich feedstock (Tamarindus Indica L.) as the precursor.
Samar Salem +2 more
doaj +2 more sources
Clinical Research for Inherited Retinal Disease Related Pediatric Blindness: A Preliminary Descriptive Analysis Based on ClinicalTrials.gov [PDF]
Journal of Multidisciplinary HealthcareAhmed M Ashour,1,2 Maan H Harbi,1 Fahad S Alshehri,1,2 Saad M Wali,1 Mohammed M Aldurdunji,3 Nasser M Alorfi1 1Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia; 2King Salman Center for ...
Ashour AM +5 more
doaj +2 more sources
Dantrolene corrects cellular disease features of Darier disease and may be a novel treatment [PDF]
EMBO Molecular MedicineDarier disease (DD) is a rare severe acantholytic skin disease caused by mutations in the ATP2A2 gene that encodes for the sarco/endoplasmic reticulum calcium ATPase isoform 2 (SERCA2).
Matthew Hunt +16 more
doaj +2 more sources
Comparison of dantrolene sodium and diazepam in the treatment of spasticity. [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1976 The effects of dantrolene sodium and diazepam were compared in a double crossover study of 42 patients with spasticity due to stable multiple sclerosis. Both drugs reduced the findings of spasticity, clonus, and hyperreflexia, and the complaints of muscle stiffness and cramping.
R T Schmidt, R H Lee, Rainer Spehlmann
openalex +4 more sources
Dantrolene Sodium Suspension in Treatment of Spastic Cerebral Palsy [PDF]
Journal of Pediatric Orthopaedics, 1980 SUMMARYA double‐blind study was carried out on 20 children with spasticity secondary to cerebral palsy, in order to compare the effects of dantrolene sodium suspension and a placebo. The drug was found to be physiologically active in reducing the force of muscle contraction, but objective functional improvement, as measured by multiple performance ...
Robert L. Joynt, James A. Leonard
openalex +6 more sources
Dantrolene sodium for treatment of carbon monoxide poisoning [PDF]
BMJ, 1988 J.B. Holter, Ronald L. L. A. Schellens
openalex +5 more sources