Novel Treatment Using Intravenous Dantrolene Sodium for Postoperative Exacerbated Spasticity in Multiple Sclerosis: A Case Report. [PDF]
Patients with upper motor neuron disease, such as multiple sclerosis, can present with severe spasticity in the perioperative period. In most cases, this can be managed with a combination of preoperative oral medications, regional or neuraxial anesthetic
Sturgill EL, Wittwer RL.
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Dantrolene sodium fails to reverse robust brain hyperthermia induced by MDMA and methamphetamine in rats. [PDF]
Cameron-Burr KT, Bola RA, Kiyatkin EA.
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Successful management of malignant hyperthermia without dantrolene: A case report. [PDF]
Malignant hyperthermia (MH) is a rare inherited genetic disorder implicated in a life-threatening catastrophic event under general anaesthesia. In India, the total number of reported cases are of the magnitude of single digit due to lack of reporting ...
Zhang C, Wang H, Chen Z, Zhang Y.
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Dantrolene sodium or dantrolene1 is 1([5-(nitrophenyl)furfurylidend] amino) hydantoin sodium hydrate. It is indicated for use in chronic disorders characterised by skeletal muscle spasticity, such as spinal cord injury, stroke, cerebral palsy and multiple sclerosis.
R M, Pinder +3 more
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Clinical Research for Inherited Retinal Disease Related Pediatric Blindness: A Preliminary Descriptive Analysis Based on ClinicalTrials.gov [PDF]
Ahmed M Ashour,1,2 Maan H Harbi,1 Fahad S Alshehri,1,2 Saad M Wali,1 Mohammed M Aldurdunji,3 Nasser M Alorfi1 1Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia; 2King Salman Center for ...
Ashour AM +5 more
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Dantrolene corrects cellular disease features of Darier disease and may be a novel treatment
Darier disease (DD) is a rare severe acantholytic skin disease caused by mutations in the ATP2A2 gene that encodes for the sarco/endoplasmic reticulum calcium ATPase isoform 2 (SERCA2).
Matthew Hunt +16 more
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This work provides a cost-effective, environmentally benign, rapidly prepared, highly fluorescent carbon dots (CDs) using renewable antioxidants-rich feedstock (Tamarindus Indica L.) as the precursor.
Samar Salem +2 more
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Dantrolene for Control of Refractory Shivering in Severe Traumatic Brain Injury: A Case Study. [PDF]
Patient: Male, 28-year-old Final Diagnosis: Brain injury Symptoms: Refractory shivering Clinical Procedure: — Specialty: Neurosurgery Objective: Unusual clinical course Background: Hyperthermia is strongly associated with a worse neurological outcome in ...
Kuboyama A +6 more
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95 Safety and Efficacy of Dantrolene Sodium (250 mg/5 mL) in Patients With Exertional Heat Stroke [PDF]
Adrian Hepner, Marna Rayl Greenberg
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