Results 11 to 20 of about 1,064,868 (260)

Novel Treatment Using Intravenous Dantrolene Sodium for Postoperative Exacerbated Spasticity in Multiple Sclerosis: A Case Report. [PDF]

open access: greenA A Pract, 2018
Patients with upper motor neuron disease, such as multiple sclerosis, can present with severe spasticity in the perioperative period. In most cases, this can be managed with a combination of preoperative oral medications, regional or neuraxial anesthetic
Sturgill EL, Wittwer RL.
europepmc   +4 more sources

Successful management of malignant hyperthermia without dantrolene: A case report. [PDF]

open access: yesJ Int Med Res
Malignant hyperthermia (MH) is a rare inherited genetic disorder implicated in a life-threatening catastrophic event under general anaesthesia. In India, the total number of reported cases are of the magnitude of single digit due to lack of reporting ...
Zhang C, Wang H, Chen Z, Zhang Y.
europepmc   +2 more sources

Dantrolene Sodium

open access: yesDrugs, 1977
Dantrolene sodium or dantrolene1 is 1([5-(nitrophenyl)furfurylidend] amino) hydantoin sodium hydrate. It is indicated for use in chronic disorders characterised by skeletal muscle spasticity, such as spinal cord injury, stroke, cerebral palsy and multiple sclerosis.
R M, Pinder   +3 more
openaire   +3 more sources

Clinical Research for Inherited Retinal Disease Related Pediatric Blindness: A Preliminary Descriptive Analysis Based on ClinicalTrials.gov [PDF]

open access: yesJournal of Multidisciplinary Healthcare
Ahmed M Ashour,1,2 Maan H Harbi,1 Fahad S Alshehri,1,2 Saad M Wali,1 Mohammed M Aldurdunji,3 Nasser M Alorfi1 1Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia; 2King Salman Center for ...
Ashour AM   +5 more
doaj   +2 more sources

Dantrolene corrects cellular disease features of Darier disease and may be a novel treatment

open access: yesEMBO Molecular Medicine
Darier disease (DD) is a rare severe acantholytic skin disease caused by mutations in the ATP2A2 gene that encodes for the sarco/endoplasmic reticulum calcium ATPase isoform 2 (SERCA2).
Matthew Hunt   +16 more
doaj   +2 more sources

Transforming a traditional ethnic beverage into highly emissive CDs as a sensitive nanosensor for the anti-malignant hyperthermia drug dantrolene sodium in pharmaceuticals and plasma. An economic and sustainable approach

open access: goldTalanta Open
This work provides a cost-effective, environmentally benign, rapidly prepared, highly fluorescent carbon dots (CDs) using renewable antioxidants-rich feedstock (Tamarindus Indica L.) as the precursor.
Samar Salem   +2 more
doaj   +2 more sources

Dantrolene for Control of Refractory Shivering in Severe Traumatic Brain Injury: A Case Study. [PDF]

open access: yesAm J Case Rep
Patient: Male, 28-year-old Final Diagnosis: Brain injury Symptoms: Refractory shivering Clinical Procedure: — Specialty: Neurosurgery Objective: Unusual clinical course Background: Hyperthermia is strongly associated with a worse neurological outcome in ...
Kuboyama A   +6 more
europepmc   +2 more sources

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