Results 101 to 110 of about 1,789 (171)

Historical development of vaginal microbicides to prevent sexual transmission of HIV in women: from past failures to future hopes

Drug Design, Development and Therapy, 2017
Fernando Notario-Pérez, Roberto Ruiz-Caro, María-Dolores Veiga-Ochoa Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, Universidad Complutense de Madrid, Madrid, Spain Abstract: Infection with human ...
Notario-Pérez F, Ruiz-Caro R, Veiga-Ochoa MD   +2 more
doaj  

Perinatal outcomes associated with pre-exposure prophylaxis for HIV prevention during pregnancy: a systematic review and meta-analysis [PDF]

Background: The World Health Organization (WHO) recommends tenofovir disoproxil fumarate (TDF)-based oral pre-exposure prophylaxis (PrEP), the dapivirine vaginal ring, and long-acting intramuscular injectable cabotegravir (CAB-LA) for HIV prevention in ...
Erlwanger, Alison, Hemelaar, Joris, Kirtley, Shona, Rocroi, Isabelle   +3 more
core   +2 more sources

The role of economic evaluations in advancing HIV multipurpose prevention technologies in early-stage development

Frontiers in Reproductive Health
Product development is a high-risk undertaking, especially so when investments are prioritized for low- and middle-income countries (LMICs) where markets may be smaller, fragile, and resource-constrained.
Katerina Chapman, Sergio Torres-Rueda, Mutsumi Metzler, Bethany Young Holt, Elijah Kahn-Woods, Douglas Thornton, Gabriela B. Gomez, Gabriela B. Gomez   +7 more
doaj   +1 more source

Lessons learnt from daily oral PrEP delivery to inform national planning for PrEP ring introduction for women in low-income and middle-income countries: a qualitative inquiry of international stakeholders

BMJ Global Health
Introduction Some African countries plan to introduce and scale-up new long-acting pre-exposure prophylaxis methods (LA-PrEP), like the monthly dapivirine vaginal ring (PrEP ring) and injectable cabotegravir.
Sergio Torres-Rueda, Magdalena E Sobieszczyk, Delivette Castor, Craig J Heck, Anita Dam, Kibret Yohannes, Justine Deacon, Katharine Kripke, Kathrine Meyers, Christopher Obermeyer, Sarah Wiant, Daniela Quigee, Martha Larson, Christine Malati, Ohemaa Poku   +14 more
doaj   +1 more source

Updates on HIV Pre-exposure Prophylaxis in Latin America: Available Drugs and Implementation Status [PDF]

Latin America has reported a 9% increase in new HIV infections from 2010 to 2023. Pre-exposure prophylaxis (PrEP) is a crucial biomedical intervention for preventing HIV transmission.
Alave, Jorge, Araoz-Salinas, Julieta M., Baltodano-Calle, Maria Jose, Belanovic-Ramirez, Ivana, Campos, Victor Y.M., Gonzales-Gavancho, Christian, Gonzales-Zamora, Jose A., Ortiz-Pardo, Allison N., Ortiz-Saavedra, Brando, Quispe-Vicuña, Carlos, Reategui-Garcia, Martin E., Rios-Garcia, Wagner, Tapia, Ruth Ramon   +12 more
core   +1 more source

Pharmacokinetics of Dapivirine Transfer into Blood Plasma, Breast Milk, and Cervicovaginal Fluid of Lactating Women Using the Dapivirine Vaginal Ring

, 2020
Breastfeeding (BF) women are an important population for biomedicalHIV prevention strategies, but they are rarely included in trials. The 25-mg dapivirinevaginal ring (VR) reduced women’s risk of sexually transmitted HIV infection in twophase 3 trials conducted in Africa.
openaire   +2 more sources

Achieving HIV epidemic control through accelerating efforts to expand access to pre-exposure prophylaxis for people who inject drugs

Frontiers in Reproductive Health
The world is not on track to reach the majority of the UNAIDS 2025 targets, and people who inject drugs (PWID) continue to be left behind, hindered by counterproductive law enforcement practices, punitive laws, economic distress, and social stigma and ...
Lirica Nishimoto, Adaobi Lisa Olisa, Philip Imohi, Judy Chang, Chris Obermeyer, Dama Kabwali, Christopher Akolo   +6 more
doaj   +1 more source

Adolescent Girls and Young Women's Experiences with Disclosing Oral PrEP or Dapivirine Vaginal Ring Use: a Multi-Country Qualitative Analysis. [PDF]

AIDS Behav, 2023
Young AM, Mancuso N, Atujuna M, Tenza S, Chitukuta M, Kemigisha D, Ngure K, van der Straten A, Garcia M, Szydlo D, Soto-Torres L, Roberts ST.   +11 more
europepmc   +1 more source

PrEP and choice counselling – Insights into implementation

Journal of Public Health in Africa
Adolescent girls and young women are disproportionately affected by human immunodeficiency virus (HIV). The introduction of oral pre-exposure prophylaxis (PrEP) was a game-changer in HIV prevention.
Melanie Pleaner, Faith Musvipwa, Siphokazi Dada, Fatima A. Cholo, Catherine E. Martin, Alison Kutywayo, Vusile Butler, Saiqa Mullick   +7 more
doaj   +1 more source

Freeze-dried, mucoadhesive system for vaginal delivery of the HIV microbicide, dapivirine: optimisation by an artificial neural network [PDF]

, 2010
Kett, Victoria L., Malcolm, R. Karl, Umrethia, Manish L., Woolfson, A. David   +3 more
core   +1 more source