Results 81 to 90 of about 1,789 (171)

Vaginal Formulations for Prevention of Sexual Transmission of HIV [PDF]

open access: yes, 2018
According to UNAIDS, as there is still no effective vaccine against HIV, pre-exposure prophylasis (PrEP) is necessary to reduce its incidence. Sexual transmission rate is higher from men to women in developing countries and vertical transmission may also
Cazorla-Luna, Raúl   +4 more
core   +2 more sources

Vaginal rings for delivery of HIV microbicides

open access: yesInternational Journal of Women's Health, 2012
R Karl Malcolm, Susan M Fetherston, Clare F McCoy, Peter Boyd, Ian MajorSchool of Pharmacy, Queen's University Belfast, Belfast, UKAbstract: Following the successful development of long-acting steroid-releasing vaginal ring devices for the ...
McCoy CF   +4 more
doaj  

Highlights from the 9th IAS conference on HIV science, 23-26 July 2017, Paris, France [PDF]

open access: yes, 2017
The 9th International AIDS Society Conference on HIV Science (IAS 2017) took place at the Palais des Congrès, in Paris, France, from 23 to 26 July 2017, chaired by Linda-Gail Bekker and Jean-François Delfraissy. It was organised by the International AIDS
Barber, Tristan J   +3 more
core   +2 more sources

Review The Emerging Profile of Cross-Resistance among the Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors

open access: yesViruses, 2014
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are widely used to treat HIV-1-infected individuals; indeed most first-line antiretroviral therapies typically include one NNRTI in combination with two nucleoside analogs.
Nicolas Sluis-Cremer
doaj   +1 more source

Advancing the use of Long‐Acting Extended Delivery formulations for HIV prevention in sub‐Saharan Africa: challenges, opportunities, and recommendations

open access: yesJournal of the International AIDS Society, 2023
Introduction The burden of HIV in sub‐Saharan Africa (SSA) remains unacceptably high, and disproportionately affects girls and women. While the introduction of oral HIV pre‐exposure prophylaxis (PrEP) in 2012 revolutionized HIV prevention, its ...
Nyaradzo M. Mgodi   +6 more
doaj   +1 more source

Pooled Prevalence of Adverse Pregnancy and Neonatal Outcomes in Malawi, South Africa, Uganda, and Zimbabwe: Results From a Systematic Review and Meta-Analyses to Inform Trials of Novel HIV Prevention Interventions During Pregnancy

open access: yesFrontiers in Reproductive Health, 2021
Background: Robust data summarizing the prevalence of pregnancy and neonatal outcomes in low- and middle-income countries are critically important for studies evaluating investigational products for HIV prevention and treatment in pregnant and ...
Erica M. Lokken   +9 more
doaj   +1 more source

CCR5 antagonists used as topical microbicides modulate CCR5 expression and may potentially compound HIV infection [PDF]

open access: yes, 2017
CCR5 antagonists, such as Maraviroc (MVC) and 5P12-RANTES, are being evaluated as HIV preventatives. The advantage of these drugs is that they restrict HIV entry via CCR5 receptor.
Laux, Julie
core  

Coming of age? Women's sexual and reproductive health after twenty-one years of democracy in South Africa [PDF]

open access: yes, 2016
This paper is a sequel to a 2004 article thet reviewed South Africa's introduction of new sexual and reproductive health (SRH) and rights, laws, policies and programmes, a decade into democracy. Similarly to the previous article this paper focuses on key
Constant, D.   +7 more
core   +1 more source

In Vitro Methods for Evaluating Drug Release of Vaginal Ring Formulations—A Critical Review [PDF]

open access: yes, 2019
The vagina is a promising site for both local and systemic drug delivery and represents an interesting administration route for compounds with poor oral bioavailability.
Klein, Sandra, Tietz, Katharina
core   +1 more source

A model of HIV/AIDS population dynamics including ARV treatment and pre-exposure prophylaxis [PDF]

open access: yes, 2018
Antiretroviral treatment (ART) and oral pre-exposure prophylaxis (PrEP) have recently been used efficiently in management of HIV infection. Pre-exposure prophylaxis consists in the use of an antiretroviral medication to prevent the acquisition of HIV ...
CP Bhunu   +18 more
core   +2 more sources

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