Results 1 to 10 of about 25,202 (260)

Dapsone induced cholangitis as a part of dapsone syndrome: a case report [PDF]

open access: goldBMC Gastroenterology, 2003
Background Dapsone can rarely cause a hypersensitivity reaction called dapsone syndrome, consisting of fever, hepatitis, exfoliative dermatitis, lymphadenopathy and hemolytic anemia.
Choudhuri Gourdas   +3 more
doaj   +6 more sources

Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro [PDF]

open access: yesMolecules
Dapsone is a sulfone used in treating inflammatory skin conditions. Despite its widespread dermatological use, the pharmacological actions of dapsone remain poorly understood.
Sara Rakočević   +7 more
doaj   +2 more sources

Aortic dissection type A, common carotid artery occlusion, and stroke after dapsone for 20 years [PDF]

open access: yesJournal of Family Medicine and Primary Care
Long-term use of dapsone, a sulfone with anti-inflammatory and immunosuppressive properties, has not been previously reported in association with aortic dissection type A.
Josef Finsterer, Sounira Mehri
doaj   +2 more sources

HLA-B*13 :01 Is a Predictive Marker of Dapsone-Induced Severe Cutaneous Adverse Reactions in Thai Patients

open access: yesFrontiers in Immunology, 2021
HLA-B*13:01 allele has been identified as the genetic determinant of dapsone hypersensitivity syndrome (DHS) among leprosy and non-leprosy patients in several studies.
Patompong Satapornpong   +43 more
doaj   +1 more source

Dapsone-Induced Granulomatous Cholestatic Hepatitis Unmasked by Steroid Taper: A Case Report

open access: yesCase Reports in Gastroenterology, 2023
Introduction: Dapsone is known to cause drug-induced liver injury (DILI) but can rarely induce the formation of hepatic granulomas. We describe a patient with jaundice who demonstrated granulomas on liver biopsy in response to dapsone.
Shahana Prakash   +2 more
doaj   +1 more source

DAPSONE-INDUCED TOXIC MACULOPATHY IN LEPROSY PATIENT

open access: yesIJRETINA (International Journal of Retina), 2023
Introduction: Dapsone has been widely used as a part of multidrug therapy for leprosy patients. Ocular side effects are rare. Ocular toxicity manifestations include retinal necrosis, optic atrophy, macular infarction, bilateral exudative retinal ...
Sita Paramita Ayuningtyas   +4 more
doaj   +3 more sources

The protective effect of dapsone against ethanol-; stress-; and indomethacin-induced gastric erosion in rats

open access: yesActa Medica Iranica, 2021
Several factors contribute to the development of gastric erosions, including corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs), alcohol, and stress.
Mohammad Sheibani   +4 more
doaj   +1 more source

Bilateral exudative retinal detachments and associated choroidal detachments in a patient on dapsone: a case report

open access: yesInternational Journal of Retina and Vitreous, 2022
Background Dapsone is a synthetic sulfonamide used to treat numerous dermatologic conditions. Ocular side effects have been rarely reported and include retinal necrosis, optic atrophy, and macular infarction.
Sarah P. Dugan, Hakan Demirci
doaj   +1 more source

Efficacy of Short-Term High Dose Pulsed Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-Infections: A Report of Three Cases and Literature Review

open access: yesAntibiotics, 2022
Lyme disease and associated co-infections are increasing worldwide and approximately 20% of individuals develop chronic Lyme disease (CLD)/Post-Treatment Lyme Disease Syndrome (PTLDS) despite early antibiotics.
Richard I. Horowitz, Phyllis R. Freeman
doaj   +1 more source

Research Supporting a Pilot Study of Metronomic Dapsone during Glioblastoma Chemoirradiation

open access: yesMedical Sciences, 2021
This short note presents previous research data supporting a pilot study of metronomic dapsone during the entire course of glioblastoma treatment. The reviewed data indicate that neutrophils are an integral part of human glioblastoma pathophysiology ...
Richard E. Kast
doaj   +1 more source

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