Results 1 to 10 of about 15,491 (225)

HLA-B*13 :01 Is a Predictive Marker of Dapsone-Induced Severe Cutaneous Adverse Reactions in Thai Patients

Frontiers in Immunology, 2021
HLA-B*13:01 allele has been identified as the genetic determinant of dapsone hypersensitivity syndrome (DHS) among leprosy and non-leprosy patients in several studies.
Patompong Satapornpong, Patompong Satapornpong, Patompong Satapornpong, Jirawat Pratoomwun, Jirawat Pratoomwun, Jirawat Pratoomwun, Pawinee Rerknimitr, Pawinee Rerknimitr, Jettanong Klaewsongkram, Jettanong Klaewsongkram, Jettanong Klaewsongkram, Nontaya Nakkam, Thanyada Rungrotmongkol, Thanyada Rungrotmongkol, Parinya Konyoung, Niwat Saksit, Ajanee Mahakkanukrauh, Warayuwadee Amornpinyo, Usanee Khunarkornsiri, Therdpong Tempark, Kittipong Wantavornprasert, Pimonpan Jinda, Pimonpan Jinda, Napatrupron Koomdee, Napatrupron Koomdee, Thawinee Jantararoungtong, Thawinee Jantararoungtong, Ticha Rerkpattanapipat, Chuang-Wei Wang, Chuang-Wei Wang, Chuang-Wei Wang, Dean Naisbitt, Wichittra Tassaneeyakul, Manasalak Ariyachaipanich, Thapana Roonghiranwat, Munir Pirmohamed, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem   +43 more
doaj   +1 more source

Dapsone-Induced Granulomatous Cholestatic Hepatitis Unmasked by Steroid Taper: A Case Report

Case Reports in Gastroenterology, 2023
Introduction: Dapsone is known to cause drug-induced liver injury (DILI) but can rarely induce the formation of hepatic granulomas. We describe a patient with jaundice who demonstrated granulomas on liver biopsy in response to dapsone.
Shahana Prakash, Matthew Gosse, Tomohiro Tanaka   +2 more
doaj   +1 more source

DAPSONE-INDUCED TOXIC MACULOPATHY IN LEPROSY PATIENT

IJRETINA (International Journal of Retina), 2023
Introduction: Dapsone has been widely used as a part of multidrug therapy for leprosy patients. Ocular side effects are rare. Ocular toxicity manifestations include retinal necrosis, optic atrophy, macular infarction, bilateral exudative retinal ...
Sita Paramita Ayuningtyas, Ari Djatikusumo, Syntia Nusanti, Salmarezka Dewiputri, Mohamad Sidik   +4 more
doaj   +3 more sources

Treatment of a life-threatening dapsone intoxication

Toxicology Reports, 2023
The case report describes a case of a severe dapsone (more than 200 tablets dapsone 100 mg) and mild methotrexate intoxication (10 tablets methotrexate 10 mg) as an attempt to commit suicide, resulting in severe cyanosis with elevation in methemoglobin ...
M.H. Veerman, T. van Gelder, R. Sneijder, C. Bethlehem   +3 more
doaj   +1 more source

Dapsone is an anticatalysis for Alzheimer’s disease exacerbation

iScience, 2022
Summary: Brain inflammation generally accelerates neurodegeneration. Alzheimer’s disease (AD) triggers an innate immune response by activating a cytosolic DNA sensor cyclic-GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) signaling pathway.
Jong Hoon Lee, Badar Kanwar, Chul Joong Lee, Consolato Sergi, Michael D. Coleman   +4 more
doaj   +1 more source

The protective effect of dapsone against ethanol-; stress-; and indomethacin-induced gastric erosion in rats

Acta Medica Iranica, 2021
Several factors contribute to the development of gastric erosions, including corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs), alcohol, and stress.
Mohammad Sheibani, Sadaf Nezamoleslami, Nastaran Rahimi, Ata Abbasi, AhmadReza Dehpour   +4 more
doaj   +1 more source

Bilateral exudative retinal detachments and associated choroidal detachments in a patient on dapsone: a case report

International Journal of Retina and Vitreous, 2022
Background Dapsone is a synthetic sulfonamide used to treat numerous dermatologic conditions. Ocular side effects have been rarely reported and include retinal necrosis, optic atrophy, and macular infarction.
Sarah P. Dugan, Hakan Demirci
doaj   +1 more source

Efficacy of Short-Term High Dose Pulsed Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-Infections: A Report of Three Cases and Literature Review

Antibiotics, 2022
Lyme disease and associated co-infections are increasing worldwide and approximately 20% of individuals develop chronic Lyme disease (CLD)/Post-Treatment Lyme Disease Syndrome (PTLDS) despite early antibiotics.
Richard I. Horowitz, Phyllis R. Freeman
doaj   +1 more source

Research Supporting a Pilot Study of Metronomic Dapsone during Glioblastoma Chemoirradiation

Medical Sciences, 2021
This short note presents previous research data supporting a pilot study of metronomic dapsone during the entire course of glioblastoma treatment. The reviewed data indicate that neutrophils are an integral part of human glioblastoma pathophysiology ...
Richard E. Kast
doaj   +1 more source

Dapsone induced cholangitis as a part of dapsone syndrome: a case report

BMC Gastroenterology, 2003
Background Dapsone can rarely cause a hypersensitivity reaction called dapsone syndrome, consisting of fever, hepatitis, exfoliative dermatitis, lymphadenopathy and hemolytic anemia.
Choudhuri Gourdas, Dhingra Sadhna, Kumar Ashish, Itha Srivenu   +3 more
doaj   +1 more source