Results 51 to 60 of about 11,723 (189)

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri   +2 more
wiley   +1 more source

Treatment of multibacillary leprosy following the development of dapsone hypersensitivity syndrome

open access: yesJDVI (Journal of General Procedural Dermatology & Venereology Indonesia), 2019
Background: World Health Organization (WHO) multi-drug therapy (MDT) is the current standard treatment for leprosy. A wide range of frequency of adverse effects caused by MDT has been reported. Dapsone hypersensitivity syndrome (DHS) is a serious adverse
Sudarsono
doaj  

STUDY FOR ANTIMYCOBACTERIAL ACTIVITY OF PYATD10 DIAZINON DERIVATIVE

open access: yesФармация и фармакология (Пятигорск), 2015
We have carried out the analysis of antymicobacterial activity of PYATd10 diazinon derivative and dapsone. The capability of PYATd10 compound and dapsone drug to suppress the growth of M.lufu culture was studied by the method of serial dilutions.
A. V. Voronkov   +5 more
doaj   +1 more source

Management of Treatment Resistant EGFR Inhibitor‐Induced Papulopustular Exanthema With Isotretinoin and Dapsone

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives Epidermal growth factor receptor inhibitors (EGFRi) commonly cause papulopustular exanthemas that may compromise the success of cancer therapy. While tetracyclines are first‐line treatment, data on alternative systemic agents for refractory cases remain limited.
Ishana Dixit   +2 more
wiley   +1 more source

Dapsone-induced agranulocytosis leading to perianal abscess and death: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Dapsone (diaminodiphenylsulfone) is used for the treatment of intractable skin diseases such as pemphigus and leprosy. The side effects of Dapsone are anemia, leukopenia, and liver dysfunction.
Kitamura Nobuya   +2 more
doaj   +1 more source

Unmet Needs in Treatment Escalation for Chronic Spontaneous Urticaria: Findings From the CURE Registry

open access: yesAllergy, EarlyView.
Appropriate treatment escalation improves CSU disease control. However, only about a quarter of patients achieve a complete response, the main goal of CSU treatment. Approximately one‐third of patients clinically eligible for escalation (UCT < 12) do not receive guideline‐recommended treatment escalation and remain symptomatic on their current ...
Pavel Kolkhir   +25 more
wiley   +1 more source

An unusual case of dapsone syndrome

open access: yesIndian Dermatology Online Journal, 2011
Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases.
Mary Grace
doaj   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, EarlyView.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier   +221 more
wiley   +1 more source

Accidental dapsone ingestion leading to methemoglobinemia in a child: A case report

open access: yesJournal of Pediatric Critical Care, 2019
Dapsone is a sulfone antibacterial drug used in the treatment of Leprosy and common skin conditions such as acne. Known to cause hypersensitivity syndromes apart from adverse effects such as tachycardia, tachypnea, vomiting, hemolytic anemias and ...
Venkat Sandeep Reddy   +3 more
doaj   +1 more source

Bruton tyrosine kinase (Btk) in neutrophils is indispensable for initiating and maintaining skin inflammation in a model of pemphigoid diseases

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Bruton tyrosine kinase (Btk) is essential for B cell function. Its role in myeloid cells is less understood. Greater insights into Btk significance in myeloid cells are needed to evaluate its potential as a therapeutic target during the effector phase of antibody‐induced autoimmune diseases, where inhibiting autoantibody ...
Henning Olbrich   +7 more
wiley   +1 more source

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