Results 101 to 110 of about 27,037 (216)

Daptomycin versus vancomycin for osteoarticular infections due to methicillin-resistant Staphylococcus aureus (MRSA): a nested case-control study [PDF]

, 2014
Vancomycin is the standard antibiotic for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. While daptomycin is approved for MRSA bacteremia, its effectiveness in osteoarticular infections (OAIs) has not been established.
Babcock, Hilary M, Khair, Hani N, Liang, Stephen Y, Marschall, Jonas, McDonald, Jay R   +4 more
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Daptomycin in vitro hatékonyságának vizsgálata Enterococcus törzsekkel szemben

, 2010
Munkám során a Debreceni Egyetemen izolált 14 VRE és 15 vancomycinnel szemben érzékeny enterococcus törzs daptomycinnel szemben mutatott in vitro érzékenységét E-teszt módszerrel vizsgáltam.
Drabik, Péter Dániel
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Current use of daptomycin and systematic therapeutic drug monitoring: Clinical experience in a tertiary care institution

, 2019
Therapeutic drug monitoring (TDM) could optimise daptomycin use. However, no validated serum target levels have been established. This prospective study at a tertiary centre including hospitalised patients receiving daptomycin aimed to evaluate the ...
Bouza Santiago, Emilio, Sánchez-Somolinos, Mar, Verde, Eduardo, Juárez, Miriam, Cercenado Mansilla, Emilia, Valerio Minero, Maricela, Muñoz García, Patricia Carmen, Galar, Alicia, Burillo Albizua, Almudena, García González, Xandra   +9 more
core   +1 more source

Dose-dependent artificial prolongation of prothrombin time by interaction between daptomycin and test reagents in patients receiving warfarin: a prospective in vivo clinical study

Annals of Clinical Microbiology and Antimicrobials, 2017
Background Daptomycin has been reported to cause artificial prolongation of prothrombin time (PT) by interacting with some test reagents of PT. This prolongation was particularly prominent with high concentrations of daptomycin in vitro. However, whether
Makoto Saito, Shuji Hatakeyama, Hideki Hashimoto, Takumitsu Suzuki, Daisuke Jubishi, Makoto Kaneko, Yukio Kume, Takehito Yamamoto, Hiroshi Suzuki, Hiroshi Yotsuyanagi   +9 more
doaj   +1 more source

Pharmacokinetics and skin-tissue penetration of daptomycin in rats

, 2015
Kazuaki Matsumoto,1 Masashi Kitaoka,1 Yuko Kuroda,1 Kazuro Ikawa,2 Norifumi Morikawa,2 Junichi Sasaki,3 Osamu Iketani,4 Satoshi Iwata,4 Tetsuya Horino,5 Seiji Hori,5 Junko Kizu1 1Division of Practical Pharmacy, Keio University Faculty of Pharmacy, Tokyo,
Sasaki J, Iwata S, Matsumoto K, Kitaoka M, Kuroda Y, Iketani O, Morikawa N, Ikawa K, Horino T, Hori S, Kizu J   +10 more
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Identification of a novel ltaS mutation in daptomycin heteroresistant community-acquired methicillin-resistant Staphylococcus aureus ST72 strains in South Korea

International Journal of Infectious Diseases
Daptomycin has been used globally since 2003, with a corresponding increase in daptomycin nonsusceptible (DNS) Staphylococcus aureus. In South Korea, daptomycin became available in 2020, but emerging resistance has posed early therapeutic challenges.
Sun Hee Park, Chulmin Park, Hye-Sun Chun, Dong-Gun Lee   +3 more
doaj   +1 more source

Oligomerization of daptomycin on membranes

, 2011
Daptomycin is a lipopeptide antibiotic that kills Gram-positive bacteria by membrane depolarization. While it has long been assumed that the mode of action of daptomycin involves the formation of membrane-associated oligomers, this has so far not been ...
Jawad K. Muraih, Jared Silverman, Muraih, Jawad K., Silverman, Jared, Andre Pearson, Palmer, Michael, Pearson, Andre, Michael Palmer   +7 more
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Bone penetration of daptomycin in diabetic patients with bacterial foot infections

International Journal of Infectious Diseases, 2019
Objectives: Daptomycin has shown clinical efficacy in diabetic foot infections (DFI). However, only limited data are available on its bone penetration in this particular population. The aim of this study was to determine daptomycin bone concentrations in
Antoine Grillon, Xavier Argemi, Jeannot Gaudias, Cécile Ronde-Ousteau, Cyril Boeri, Jean-Yves Jenny, Yves Hansmann, Nicolas Lefebvre, François Jehl   +8 more
doaj   +1 more source

High-dose, short-interval daptomycin regimen was safe and well tolerated in three patients with chronic renal failure

, 2013
Kaori Yabuno,1,2,* Masafumi Seki,1,* Koji Miyawaki,1,2 Yoshihiro Miwa,2 Kazunori Tomono11Division of Infection Control and Prevention, 2Department of Pharmacy, Osaka University Hospital, Osaka, Japan *These authors contributed equally to this ...
Yabuno K, Miyawaki K, Miwa Y, Seki M, Tomono K   +4 more
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Phosphate Ions Alter the Binding of Daptomycin to Living Cell Membranes

, 2020
Advancements in antibiotic drug design are often hindered by missing information in how these small molecules interact with living cells. The antibiotic, daptomycin, has found clinical success, and emerging resistance, but a comprehensive picture of its ...
Tessa, Calhoun, Lindsey, Miller
core   +1 more source