Results 81 to 90 of about 21,016 (175)

Daptomycin versus linezolid for the treatment of vancomycin-resistant enterococcal bacteraemia: implications of daptomycin dose

open access: yes, 2017
Treatment options for vancomycin-resistant enterococci (VRE) bloodstream infection are limited. Studies comparing daptomycin or linezolid in treating VRE bloodstream infection have conflicting results and suggest daptomycin underdosing.
Chuang, Y-C.;Lin, H-Y.;Chen, P-Y.;Lin, C-Y.;Wang, J-T.;Chang, S-C.   +1 more
core   +1 more source

Daptomycin-Nonsusceptible, Vancomycin-Intermediate, Methicillin-Resistant Staphylococcus aureus Endocarditis

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2012
Due to the emergence of Staphylococcus aureus with reduced vancomycin susceptibility, newer antibiotics, including daptomycin, have been used to treat methicillin-resistant S aureus infections. Daptomycin is a cyclic lipopeptide that is approved to treat
Ryan Yu   +4 more
doaj   +1 more source

Defective pgsA contributes to increased membrane fluidity and cell wall thickening in Staphylococcus aureus with high-level daptomycin resistance

open access: yesmSphere
Daptomycin is a membrane-targeting last-resort antimicrobial therapeutic for the treatment of infections caused by methicillin- and/or vancomycin-resistant Staphylococcus aureus. In the rare event of failed daptomycin therapy, the source of resistance is
Christian D. Freeman   +5 more
doaj   +1 more source

Daptomycin in vitro hatékonyságának vizsgálata Enterococcus törzsekkel szemben

open access: yes, 2010
Munkám során a Debreceni Egyetemen izolált 14 VRE és 15 vancomycinnel szemben érzékeny enterococcus törzs daptomycinnel szemben mutatott in vitro érzékenységét E-teszt módszerrel vizsgáltam.
Drabik, Péter Dániel
core  

Pharmacokinetics and skin-tissue penetration of daptomycin in rats

open access: yes, 2015
Kazuaki Matsumoto,1 Masashi Kitaoka,1 Yuko Kuroda,1 Kazuro Ikawa,2 Norifumi Morikawa,2 Junichi Sasaki,3 Osamu Iketani,4 Satoshi Iwata,4 Tetsuya Horino,5 Seiji Hori,5 Junko Kizu1 1Division of Practical Pharmacy, Keio University Faculty of Pharmacy, Tokyo,
Sasaki J   +10 more
core  

Daptomycin approved in Japan for the treatment of methicillin-resistant Staphylococcus aureus [PDF]

open access: yes, 2012
Mao Hagihara1, Takumi Umemura1, Takeshi Mori1,2, Hiroshige Mikamo11Department of Infection Control and Prevention, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan; 2Division of Pharmaceutical Science, Faculty of Pharmacy, Meijo ...
Hagihara M, Mikamo H, Mori T, Umemura T
core  

Identification of a novel ltaS mutation in daptomycin heteroresistant community-acquired methicillin-resistant Staphylococcus aureus ST72 strains in South Korea

open access: yesInternational Journal of Infectious Diseases
Daptomycin has been used globally since 2003, with a corresponding increase in daptomycin nonsusceptible (DNS) Staphylococcus aureus. In South Korea, daptomycin became available in 2020, but emerging resistance has posed early therapeutic challenges.
Sun Hee Park   +3 more
doaj   +1 more source

Daptomycin exposure precedes infection and/or colonization with daptomycin non-susceptible enterococcus [PDF]

open access: yes, 2012
Background Daptomycin non-susceptible enterococci (DNSE) are emerging as an important cause of healthcare-associated infection, however little is known about the epidemiology of DNSE.
Sarah J Johnson   +9 more
core   +1 more source

Bone penetration of daptomycin in diabetic patients with bacterial foot infections

open access: yesInternational Journal of Infectious Diseases, 2019
Objectives: Daptomycin has shown clinical efficacy in diabetic foot infections (DFI). However, only limited data are available on its bone penetration in this particular population. The aim of this study was to determine daptomycin bone concentrations in
Antoine Grillon   +8 more
doaj   +1 more source

Addition of daptomycin to levofloxacin increased the efficacy of levofloxacin monotherapy against a methicillin-susceptible Staphylococcus aureus strain in experimental meningitis and prevented development of resistance in vitro.

open access: yes, 2022
Introduction. Daptomycin and levofloxacin were tested as monotherapies and in combination against the antibiotic-susceptible S. aureus strain MSSA 1112 in a rabbit meningitis model and the effect of the combination on induction of resistance was ...
Collaud, Alexandra   +5 more
core   +1 more source

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