Results 81 to 90 of about 29,458 (191)

Of Commensals and Opportunists: Genomics of Coagulase‐Negative Staphylococci During Sequential Ear and Eye Infections in a Healthy Adult

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
The genomes of coagulase‐negative staphylococci (CoNS) isolated during sequential ear and eye infections in a healthy adult are analyzed. We highlight the identification of a community‐acquired S. capitis subsp. urealyticus ST1 lineage carrying a mosaic SCCmec IV element, linking common skin commensals to multidrug‐resistant strains associated with ...
Soo Sum Lean, Chew Chieng Yeo, Zain Illyaaseen, Sargit Kaur, Yun Fong Ngeow, Stuart C. Clarke, Hien Fuh Ng   +6 more
wiley   +1 more source

Genomic Insights Into a Hospital‐Acquired High‐Risk Vancomycin‐Resistant Enterococcus faecium Outbreak in Guangdong, China

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
We characterized a dominant ST80 clone responsible for a vancomycin‐resistant Enterococcus faecium outbreak in Chinese hospitals, revealing its close genetic ties to global lineages. A novel PCR method was developed for targeted surveillance of this high‐risk strain. ABSTRACT A comprehensive molecular epidemiological study was conducted on a vancomycin‐
Yang Guo, Chuyue Zhuo, Tianxin Zhang, Kuihai Wu, Zhengqi Shi, Yan Zhu, Jiayuan Huang, Chao Zhuo, Nan Qi   +8 more
wiley   +1 more source

Daptomycin resistance of Corynebacterium jeikeium due to pgsA gene mutation acquired during daptomycin treatment in a patient with infective endocarditis

International Journal of Infectious Diseases
Daptomycin is an alternative agent for invasive infections caused by Corynebacterium species in patients with intolerance to vancomycin. Although it has recently been recognized that treatment failure with daptomycin due to the emergence of resistant ...
Makoto Inada, Kohji Komori, Sohei Harada, Shinya Yamamoto, Koh Okamoto, Ayano Nakazato, Yoshimi Higurashi, Shuhei Matsumoto, Junji Tokushige, Arika Shimura, Takeya Tsutsumi   +10 more
doaj   +1 more source

Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model. [PDF]

, 2019
Introduction:Treatment of open fractures routinely involves multiple surgeries and delayed definitive fracture fixation because of concern for infection.
Bernthal, NM, Hegde, V, Loftin, AH, Niska, J, Segura, T, Stavrakis, AI, Weixian, X, Zhu, S   +7 more
core  

New intravenous antibiotics: a focused pharmacotherapy update [PDF]

, 2010
Infections due to multidrug-resistant pathogens are increasing throughout the world, in particular due to the emergence of resistant Staphylococcus aureus, vancomycin-resistant enterococcus (VRE) penicillin-resistant Streptococcus pneumonia, multidrug ...
Connor, Kathryn A
core   +3 more sources

Comprehensive Analysis of Structure Activity Relationships in Quinoxaline Derivatives Covering Antimicrobial Applications

ChemistrySelect, Volume 11, Issue 14, 13 April 2026.
ABSTRACT Antimicrobial resistance (AMR) has emerged as one of the most critical global health challenges, undermining the clinical efficacy of existing antibiotics and threatening modern therapeutic strategies. The ongoing misuse and overuse of antimicrobial agents have accelerated the evolution of resistant bacterial strains and parasites ...
Subham Kumar Vishwakarma, Fernando Rogério Pavan, Cesar Augusto Roque‐Borda   +2 more
wiley   +1 more source

Identification and Characterisation of the Gene Cluster Governing Biosynthesis of the Anti‐Mycobacterial Antibiotic Acidomycin

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Biosynthetic gene cluster for antibiotic acidomycin targeting biotin biosynthesis in mycobacteria was identified in a Streptomyces bacterium, and its identity was confirmed by gene knockout and heterologous expression. This cluster is located in proximity to the genes cluster for stravidins targeting a different step in the biotin biosynthesis pathway.
Anna Vignolle, Martin Zehl, Jaime Felipe Guerrero Garzón, Olha Schneider, Johannes Gafriller, Ulrike Grienke, Rasmus H. Kirkegaard, Sergey B. Zotchev   +7 more
wiley   +1 more source

Daptomycin-Nonsusceptible, Vancomycin-Intermediate, Methicillin-Resistant Staphylococcus aureus Endocarditis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2012
Due to the emergence of Staphylococcus aureus with reduced vancomycin susceptibility, newer antibiotics, including daptomycin, have been used to treat methicillin-resistant S aureus infections. Daptomycin is a cyclic lipopeptide that is approved to treat
Ryan Yu, Suzanne E Dale, Deborah Yamamura, Vida Stankus, Christine Lee   +4 more
doaj   +1 more source

Efficacy of daptomycin in the treatment of experimental endocarditis due to susceptible and multidrug-resistant enterococci [PDF]

, 2017
Objectives: Daptomycin was tested in vitro and in rats with experimental endocarditis against the ampicillin-susceptible and vancomycin-susceptible Enterococcus faecalis JH2-2, the vancomycin-resistant (VanA type) mutant of strain JH2-2 (strain JH2-2 ...
Entenza, José M., Giddey, Marlyse, Moreillon, Philippe, Vouillamoz, Jacques   +3 more
core  

Comprehensive Management of Diabetic Foot Ulcers: Current Evidence and Practice

Journal of Diabetes, Volume 18, Issue 4, April 2026.
This figure illustrates a multidisciplinary approach to the management of diabetic foot ulcers, including wound care, metabolic management, infection control, vascular intervention, and surgical treatment. Integration of these components is essential for optimizing healing, preventing complications, and preserving the limb.
Ji Min Kim, Seon Mee Kang, Jung Hwa Jung, Ki Chun Kim, Sanghyun Ahn, Chong Hwa Kim, Tae Sun Park, Ie Byung Park   +7 more
wiley   +1 more source