Results 71 to 80 of about 21,016 (175)

Daptomycin non-susceptible Enterococcus faecium in leukemia patients: Role of prior daptomycin exposure [PDF]

, 2016
OBJECTIVES: We sought to determine the association between previous daptomycin exposure and daptomycin non-susceptible Enterococcus faecium (DNSEf) bloodstream infections (BSI) in adult leukemia patients. METHODS: We retrospectively identified adult (≥
Tverdek, Frank, Arias, Cesar, Aitken, Samuel L., Tarrand, Jeffrey, DiPippo, Adam, Shelburne, Samuel, Tran, Truc, Munita, José   +7 more
core   +1 more source

In vitro persistence of clinical methicillin-resistant Staphylococcus aureus isolates from bone and joint infections after exposure to daptomycin, telavancin, and vancomycin

Microbiology Spectrum
Bacterial persistence is linked to chronic infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Understanding the persister profiles of daptomycin, telavancin, and vancomycin is crucial because MRSA bone and joint infections (BJIs ...
Aliaa Fouad, Joseph L. Kuti, Christian M. Gill   +2 more
doaj   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

Advanced Science, Volume 13, Issue 50, 7 September 2026.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen, Jiayi Liang, Yujia Wu, Jianan Xu, Yi Liu, Wenguang Wang, Xinhang Jiang, Benjie Gao, Yueyue Wang, Hui Jiang   +9 more
wiley   +1 more source

A daptomycin biotechnológiai úton történő előállítása

, 2013
A daptomycin, egy lipopeptid antibiotikum bemutatása és fermentáció általi előállításának ismertetése. Szó esik a dolgozatban a gyártáshoz használt Streptomyces roseosporusról és rövid ismertetése is megtörténik.
Kerekes, Fanni
core  

Daptomycin–β-Lactam Combinations in a Rabbit Model of Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Endocarditis [PDF]

, 2016
Beta-lactams enhance the in vitro activity of daptomycin against methicillin-resistant strains of Staphylococcus aureus Experiments were performed in a rabbit model of aortic valve endocarditis caused by methicillin-resistant daptomycin-nonsusceptible S.
Hamilton, Stephanie M, Chambers, Henry F, Choo, Eun Ju, Moise, Pamela, Basuino, Li   +4 more
core   +1 more source

Severe Multiorgan Failure Triggered by Infection in an Adult With Decades of Untreated Sickle Cell Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 67‐year‐old man with decades of untreated sickle cell disease developed septic shock with multiorgan failure, splenic infarction, and marrow fibrosis; his genotype could not be confirmed. He recovered with intensive supportive care, with hydroxyurea initiated for long‐term disease modification, illustrating catastrophic infection‐triggered ...
Sara Shahidi, Gisha Mohan
wiley   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Long‐Term Use of Rezafungin: A Case Report and Insights Into Real‐World Access

Transplant Infectious Disease, EarlyView.
Jian Mei Li, Jacqueline E. Clark, Tiffany Wu   +2 more
wiley   +1 more source

Differentiating Normal Healing From Infection in Total Joint Arthroplasty: An Educational and Diagnostic Tool for Emergency Providers Evaluating the Postoperative Patient

Academic Emergency Medicine, Volume 33, Issue 9, September 2026.
ABSTRACT Patients frequently present to the emergency department (ED) with pain, swelling, or erythema in the early period following total joint arthroplasty (TJA). Differentiating normal postoperative inflammation from superficial surgical site infection (S‐SSI) or early periprosthetic joint infection (PJI) can be difficult due to overlapping clinical
Thomas W. Brown, Andrew T. Carusi, Michael Langworthy   +2 more
wiley   +1 more source

Development of pilot plant fermentation in the pharmaceutical industry – active pharmaceutical ingredient: Daptomycin

, 2016
A daptomycin nevű antibiotikum termeltetésének kísérleti üzemi léptékű fejlesztése, a technológia optimalizálása. A dolgozat célkitűzése volt: a technológia reprezentatív módon történő bemutatása, a daptomycin kihozatalának növelése, a hatóanyag mellett ...
Anga, Csilla
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