Results 51 to 60 of about 27,037 (216)
BMC Pharmacology and Toxicology, 2019 Background Daptomycin is an important drug used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection. A high dose of daptomycin is indicated for an MRSA infection with a minimum inhibitory concentration (MIC) of 1 mg/L for ...
Yi-Chien Lee +3 more
doaj +1 more source
Antimicrobial Agents and Chemotherapy, 2019 Vancomycin (VAN) and daptomycin (DAP) are approved as a monotherapy for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. A regimen of daptomycin plus ceftaroline (DAP+CPT) has shown promise in published case series of MRSA salvage therapy ...
M. Geriak +11 more
semanticscholar +1 more source
Evaluating the Rapid Emergence of Daptomycin Resistance in Corynebacterium: a Multicenter Study
Journal of Clinical Microbiology, 2021 Members of the genus Corynebacterium are increasingly recognized as pathobionts and can be very resistant to antimicrobial agents. Previous studies have demonstrated that Corynebacterium striatum can rapidly develop high-level daptomycin resistance (HLDR)
Kaitlin F. Mitchell +6 more
semanticscholar +1 more source
Frontiers in Microbiology, 2022 Growing evidence has shown that the efficacy of systemic administration of daptomycin for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-related infections is satisfactory.
Xin Zhang +11 more
doaj +1 more source
Structure-activity relationships of daptomycin lipopeptides.
Journal of Medicinal Chemistry, 2020 Daptomycin is a calcium-dependent cyclic lipodepsipeptide derived from the soil saprotroph Streptomyces roseosporus and its antibiotic properties make it a key agent for treatment of drug-resistant Gram-positive infections.
J. Karas +8 more
semanticscholar +1 more source
Antibiotics, 2021 Introduction: E. faecium and E. faecalis are responsible for 13.9% of hospital-acquired infections with frequent resistance to vancomycin (82.6% of E. faecium, 9.5% of E. faecalis).
Katie E. Barber +5 more
semanticscholar +1 more source
Antibiotics, 2019 This study assesses the synergistic effect of the combination of cephalosporins and sulbactam with daptomycin against daptomycin-nonsusceptible, vancomycin-intermediate resistant Staphylococcus aureus (VISA) or heterogeneous vancomycin-intermediate S ...
Chih-Cheng Lai +8 more
doaj +1 more source
Brazilian Journal of Infectious Diseases, 2013 Objectives: To collect data about non-controlled prescribing use of daptomycin and its impact among Brazilian patients with serious Gram positive bacterial infection, as well as the efficacy and safety outcomes.
Artur Timerman +7 more
doaj +3 more sources
Optimizing Daptomycin Dosing: Environmental Benefit and Cost Savings
Antimicrobial Stewardship & Healthcare EpidemiologyBackground: The pharmaceutical industry is estimated to have a larger environmental footprint than the automotive industry. Discarded and unused doses of pharmaceuticals generate financial waste and pollution, and exacerbate antibiotic shortages.
Pamela Lee +4 more
doaj +1 more source
, 2017 Background: Linezolid, which has bacteriostatic activity, is approved for the treatment of vancomycin-resistant enterococci (VRE) infections. Meanwhile, daptomycin exerts bactericidal activity against VRE, but is not approved for the treatment of VRE ...
Chuang, Yu-Chung;Wang, Jann-Tay;Lin, Hsin-Yi;Chang, Shan-Chwen +1 more
core +1 more source