Results 51 to 60 of about 29,458 (191)

Comprehensive and Comparative Transcriptional Profiling of the Cell Wall Stress Response in Bacillus subtilis

open access: yesMolecular Microbiology, EarlyView.
Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang   +12 more
wiley   +1 more source

Daptomycin Resistance in Clinical MRSA Strains Is Associated with a High Biological Fitness Cost

open access: yesFrontiers in Microbiology, 2017
Daptomycin remains as one of the main treatment options for Methicillin-Resistant Staphylococcus aureus (MRSA). Sporadic resistance cases reported in patients treated with either daptomycin or glycopeptides are a growing concern.
Melanie Roch   +8 more
doaj   +1 more source

Cardiolipin Prevents Membrane Translocation and Permeabilization by Daptomycin [PDF]

open access: yes, 2014
This research was originally published in Journal of Biological Chemistry. Zhang, T., Muraih, J. K., Tishbi, N., Herskowitz, J., Victor, R. L., Silverman, J., … Mintzer, E. (2014).
Herskowitz, Jennifer   +9 more
core   +2 more sources

Engineered surface strategies to manage dental implant‐related infections

open access: yesPeriodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza   +7 more
wiley   +1 more source

The action mechanism of daptomycin [PDF]

open access: yes, 2016
The final publication is available at Elsevier via http://dx.doi.org/10.1016/j.bmc.2016.05.052 © 2016.Daptomycin is a lipopeptide antibiotic produced by the soil bacterium Streptomyces roseosporus that is clinically used to treat severe infections with ...
Palmer, Michael, Taylor, Scott D.
core   +1 more source

No Increased Risk of Infection Following a Protocol Change to Decrease Duration of Perioperative Antibiotic Prophylaxis in Liver Transplantation

open access: yesTransplant Infectious Disease, EarlyView.
There was no increased rate of surgical site infection or bacteremia in liver transplant recipients following a decrease in perioperative antibiotic prophylaxis duration, with a change from 2.4% to 2.8% in patients hospitalized prior to transplant and 7.5% to 2.9% in other patients.
Hutton Brandon   +4 more
wiley   +1 more source

Activity of daptomycin- and vancomycin-loaded poly-epsilon-caprolactone microparticles against mature staphylococcal biofilms. [PDF]

open access: yes, 2015
The aim of the present study was to develop novel daptomycin-loaded poly-epsilon-caprolactone (PCL) microparticles with enhanced antibiofilm activity against mature biofilms of clinically relevant bacteria, methicillin-resistant Staphylococcus aureus ...
Almeida, A.J.   +8 more
core   +1 more source

Multidisciplinary Approach to Complex Lower Extremity Limb Salvage in Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome: A Case Report

open access: yesMicrosurgery, Volume 46, Issue 4, May 2026.
ABSTRACT Limb salvage using free tissue transfer in patients with rare autoinflammatory syndromes is poorly described, and the safety of microvascular reconstruction in this population remains uncertain. Hereditary pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome is characterized by dysregulated inflammation, pathergy, and impaired ...
Michael M. Talanker   +9 more
wiley   +1 more source

Daptomycin: a comparison of two intravenous formulations

open access: yesDrug Design, Development and Therapy, 2018
Celeste Frankenfeld, Sachin Mittal, Yanira Melendez, Luke Mendez-Vigo, Kenneth C Lamp, Kaitlin N Keller, Shellie R Bertolami Merck & Co., Inc., Kenilworth, NJ, USA Abstract: Daptomycin is a cyclic lipopeptide antibacterial agent with potent ...
Frankenfeld C   +6 more
doaj  

Transfer of antibiotic resistance in Staphylococcus aureus [PDF]

open access: yes, 2017
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob   +2 more
core   +1 more source

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