Results 41 to 50 of about 27,037 (216)
Frontiers in Pharmacology, 2022 Background and Objective: Daptomycin is used to treat Gram-positive infections in adults and children and its dosing varies among different age groups. We focused on the pharmacokinetics of daptomycin in children with renal impairment, which has not been
Lingling Ye +7 more
doaj +1 more source
In Vivo Efficacy of Daptomycin against Methicillin-Resistant Staphylococcus aureus in a Mouse Model of Hematogenous Pulmonary Infection [PDF]
, 2013 Daptomycin is inactivated by pulmonary surfactant, but its effectiveness in hematogenous pulmonary infection has been poorly studied. The potential therapeutic application was evaluated in a methicillin-resistant Staphylococcus aureus (MRSA) hematogenous
Yamada, Koichi +13 more
core +1 more source
Antibiotics, 2020 Daptomycin is a cyclic lipopeptide antibiotic, which was discovered in 1987 and entered the market in 2003. To date, it serves as last resort antibiotic to treat complicated skin infections, bacteremia, and right-sided endocarditis caused by Gram ...
D. A. Gray, Michaela Wenzel
semanticscholar +1 more source
Frontiers in Microbiology, 2021 Vancomycin-resistant Enterococcus faecium (VREF) and methicillin-resistant Staphylococcus aureus (MRSA) are associated with significant health burden. We investigated linezolid and daptomycin resistance among VREF and MRSA in the EU/EEA between 2014 and ...
Robby Markwart +4 more
semanticscholar +1 more source
High-Dose Daptomycin and Clinical Applications
The Annals of Pharmacotherapy, 2021 Objective: To evaluate evidence for high-dose daptomycin (doses ≥ 8 mg/kg/d). Data Sources: A PubMed/MEDLINE literature search was performed (January 2000 to December 2020) using the search terms daptomycin, high dose, and dosing.
Timothy W. Jones +3 more
semanticscholar +1 more source
ACS Infectious Diseases, 2021 Multidrug-resistant bacteria pose a serious global health threat as antibiotics are increasingly losing their clinical efficacy. A molecular level understanding of the mechanism of action of antimicrobials plays a key role in developing new agents to ...
Ioli Kotsogianni +4 more
semanticscholar +1 more source
Antibiotics, 2021 Background: Daptomycin-induced eosinophilic pneumonia (DEP) is a rare but severe adverse effect and the risk factors are unknown. The aim of this study was to determine risk factors for DEP. Methods: A retrospective cohort study was performed at the Bone
Laura Soldevila-Boixader +8 more
semanticscholar +1 more source
Acute Angioedema Triggered by Daptomycin. [PDF]
, 2016 INTRODUCTION Daptomycin is a cyclic lipopeptide antibiotic, frequently administered for Staphylococcus aureus bloodstream infections. Numerous studies have shown that daptomycin is relatively safe and well tolerated.
Lionel Müller +9 more
core +1 more source
Evaluation of pharmacokinetics and the stability of daptomycin in serum at various temperatures
International Journal of Infectious Diseases, 2017 Background: Daptomycin exhibits concentration-dependent antibacterial activity. By monitoring daptomycin serum concentrations, clinicians may be able to predict the effectiveness of treatments for infections more accurately. However, it has been reported
Chika Ogami +7 more
doaj +1 more source
Open Forum Infectious Diseases, 2021 Background Observational data suggest ceftaroline may be effective for methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI), but comparative data with standard of care are limited. This analysis compares the outcomes of MRSA BSI
E. Zasowski +15 more
semanticscholar +1 more source