Results 21 to 30 of about 21,016 (175)

Acute Angioedema Triggered by Daptomycin. [PDF]

, 2016
INTRODUCTION Daptomycin is a cyclic lipopeptide antibiotic, frequently administered for Staphylococcus aureus bloodstream infections. Numerous studies have shown that daptomycin is relatively safe and well tolerated.
Lionel Müller, Sabine Müller, Müller, Lionel, Jörg-Walther, Lukas, Parham Sendi, Lukas Jörg-Walther, Sendi, Parham, Gisler, Valentin, Müller, Sabine, Valentin Gisler   +9 more
core   +2 more sources

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +2 more sources

Evaluation of pharmacokinetics and the stability of daptomycin in serum at various temperatures

International Journal of Infectious Diseases, 2017
Background: Daptomycin exhibits concentration-dependent antibacterial activity. By monitoring daptomycin serum concentrations, clinicians may be able to predict the effectiveness of treatments for infections more accurately. However, it has been reported
Chika Ogami, Yasuhiro Tsuji, Hidefumi Kasai, Yoichi Hiraki, Yoshihiro Yamamoto, Kazuhisa Matsunaga, Yoshiharu Karube, Hideto To   +7 more
doaj   +1 more source

A study on combination of daptomycin with selected antimicrobial agents: in vitro synergistic effect of MIC value of 1 mg/L against MRSA strains

BMC Pharmacology and Toxicology, 2019
Background Daptomycin is an important drug used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection. A high dose of daptomycin is indicated for an MRSA infection with a minimum inhibitory concentration (MIC) of 1 mg/L for ...
Yi-Chien Lee, Pao-Yu Chen, Jann-Tay Wang, Shan-Chwen Chang   +3 more
doaj   +1 more source

Antimicrobial potency, prevention ability, and killing efficacy of daptomycin-loaded versus vancomycin-loaded β-tricalcium phosphate/calcium sulfate for methicillin-resistant Staphylococcus aureus biofilms

Frontiers in Microbiology, 2022
Growing evidence has shown that the efficacy of systemic administration of daptomycin for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-related infections is satisfactory.
Xin Zhang, Xin Zhang, Peng Chen, Peng Chen, Hao-yang Wan, Run-jiu Zhu, Yue Zhou, Ming-rui Song, Nan Jiang, Nan Jiang, Bin Yu, Bin Yu   +11 more
doaj   +1 more source

Hypothesis: daptomycin permeabilizes membranes by forming self‑assembled nanotubes [PDF]

, 2020
Daptomycin is the only lipopeptide antibiotic that is widely used in clinical practice. It was discovered by Eli Lilly and then studied and commercialized by Cubist Pharmaceuticals in 2003.
A. Zhivich
core   +1 more source

Evaluating the safety of daptomycin coadministered with statin medicationsKey Points Background:

JAPhA Pharmacotherapy
Background: Conflicting clinical evidence and prescribing recommendations exist regarding the safety of daptomycin when coadministered with statin medications.
Tyler M. Mitzner, Michael McCormick, Krissy M. Lentz, Ryan Tomlin, Kyle J. Schmidt, Lisa E. Dumkow   +5 more
doaj   +1 more source

The Potential Role of Sulbactam and Cephalosporins Plus Daptomycin Against Daptomycin-Nonsusceptible VISA and H-VISA Isolates: An In Vitro Study

Antibiotics, 2019
This study assesses the synergistic effect of the combination of cephalosporins and sulbactam with daptomycin against daptomycin-nonsusceptible, vancomycin-intermediate resistant Staphylococcus aureus (VISA) or heterogeneous vancomycin-intermediate S ...
Chih-Cheng Lai, Chi-Chung Chen, Ying-Chen Lu, Tsuey-Pin Lin, Hung-Jui Chen, Bo-An Su, Chien-Ming Chao, Yin-Ching Chuang, Hung-Jen Tang   +8 more
doaj   +1 more source

Brazilian experience in EU-CORE: daptomycin registry and treatment of serious Gram-positive infections

Brazilian Journal of Infectious Diseases, 2013
Objectives: To collect data about non-controlled prescribing use of daptomycin and its impact among Brazilian patients with serious Gram positive bacterial infection, as well as the efficacy and safety outcomes.
Artur Timerman, Carlos Brites, Eliana Bicudo, Renato S. Grinbaum, Rubens Costa Filho, Claudia D.M. Carrilho, Andre Bichels, Tânia Barreto   +7 more
doaj   +3 more sources

Optimizing Daptomycin Dosing: Environmental Benefit and Cost Savings

Antimicrobial Stewardship & Healthcare Epidemiology
Background: The pharmaceutical industry is estimated to have a larger environmental footprint than the automotive industry. Discarded and unused doses of pharmaceuticals generate financial waste and pollution, and exacerbate antibiotic shortages.
Pamela Lee, Marina Nguyen, Michelle LeBrun, Gary Fong, Loren Miller   +4 more
doaj   +1 more source