Results 21 to 30 of about 29,458 (191)
Enterococcal periprosthetic joint infection: clinical and microbiological findings from an 8-year retrospective cohort study [PDF]
, 2019 BACKGROUND: Treatment of enterococcal periprosthetic joint infections (PJI) is challenging due to non-standardized management strategies and lack of biofilm-active antibiotics. The optimal surgical and antimicrobial therapy are unknown.
Akgün, Doruk +4 more
core +1 more source
Impact of time to appropriate therapy on mortality in patients with vancomycin-intermediate Staphylococcus aureus infection [PDF]
, 2016 Despite the increasing incidence of vancomycin-intermediate Staphylococcus aureus (VISA) infections, few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in VISA patients.
Burnham, Carey-Ann D +3 more
core +2 more sources
Frontiers in Microbiology, 2022 Growing evidence has shown that the efficacy of systemic administration of daptomycin for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-related infections is satisfactory.
Xin Zhang +11 more
doaj +1 more source
Multicenter Study of High-Dose Daptomycin for Treatment of Enterococcal Infections [PDF]
, 2013 Enterococci are among the leading pathogens isolated in hospital-acquired infections. Current antimicrobial options for vancomycin-resistant enterococci (VRE) are limited.
Casapao, Anthony M. +11 more
core +2 more sources
Evaluation of pharmacokinetics and the stability of daptomycin in serum at various temperatures
International Journal of Infectious Diseases, 2017 Background: Daptomycin exhibits concentration-dependent antibacterial activity. By monitoring daptomycin serum concentrations, clinicians may be able to predict the effectiveness of treatments for infections more accurately. However, it has been reported
Chika Ogami +7 more
doaj +1 more source
Risk factors for failure of outpatient parenteral antibiotic therapy (OPAT) in infective endocarditis [PDF]
, 2013 Objectives: To identify risk factors for failure of outpatient antibiotic therapy (OPAT) in infective endocarditis (IE). Patients and methods: We identified IE cases managed at a single centre over 12 years from a prospectively maintained database. ‘
Barr, D. A. +5 more
core +1 more source
BMC Pharmacology and Toxicology, 2019 Background Daptomycin is an important drug used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection. A high dose of daptomycin is indicated for an MRSA infection with a minimum inhibitory concentration (MIC) of 1 mg/L for ...
Yi-Chien Lee +3 more
doaj +1 more source
Antibiotics, 2019 This study assesses the synergistic effect of the combination of cephalosporins and sulbactam with daptomycin against daptomycin-nonsusceptible, vancomycin-intermediate resistant Staphylococcus aureus (VISA) or heterogeneous vancomycin-intermediate S ...
Chih-Cheng Lai +8 more
doaj +1 more source
Brazilian Journal of Infectious Diseases, 2013 Objectives: To collect data about non-controlled prescribing use of daptomycin and its impact among Brazilian patients with serious Gram positive bacterial infection, as well as the efficacy and safety outcomes.
Artur Timerman +7 more
doaj +3 more sources
Optimizing Daptomycin Dosing: Environmental Benefit and Cost Savings
Antimicrobial Stewardship & Healthcare EpidemiologyBackground: The pharmaceutical industry is estimated to have a larger environmental footprint than the automotive industry. Discarded and unused doses of pharmaceuticals generate financial waste and pollution, and exacerbate antibiotic shortages.
Pamela Lee +4 more
doaj +1 more source