Results 101 to 110 of about 727,203 (295)

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

The Impact of Foregrounds on Dark Ages Measurements with the Highly Redshifted 21 cm Line

The Astrophysical Journal
Studies of the cosmic dark ages (30 ≲  z  ≲ 150) using the highly redshifted 21 cm line of neutral hydrogen offer unparalleled amounts of cosmological information, and recent years have seen the refinement of concepts for such experiments (e.g., CoDEX ...
Jonathan C. Pober, Willow Smith
doaj   +1 more source

Peering into the dark (ages) with low-frequency space interferometers: Using the 21-cm signal of neutral hydrogen from the infant universe to probe fundamental (Astro)physics. [PDF]

Exp Astron (Dordr), 2021
Koopmans LVE, Barkana R, Bentum M, Bernardi G, Boonstra AJ, Bowman J, Burns J, Chen X, Datta A, Falcke H, Fialkov A, Gehlot B, Gurvits L, Jelić V, Klein-Wolt M, Lazio J, Meerburg D, Mellema G, Mertens F, Mesinger A, Offringa A, Pritchard J, Semelin B, Subrahmanyan R, Silk J, Trott C, Vedantham H, Verde L, Zaroubi S, Zarka P.   +29 more
europepmc   +1 more source

Stratigraphy of the Perrine and Nun Sulci quadrangles (Jg-2 and Jg-5), Ganymede [PDF]

Dark and light terrain materials in the Perrine and Nun Sulci quadrangles are divided into nine map units, four dark, and five light. These are placed in time-stratigraphic sequence primarily by means of embayment and cross-cutting relationships.
Mcgill, George E., Squyres, Steven W.
core   +1 more source

Further evidence for large central mass-to-light ratios in early-type galaxies: the case of ellipticals and lenticulars in the Abell~262 cluster

, 2012
We present radially resolved spectroscopy of 8 early-type galaxies in Abell~262, measuring rotation, velocity dispersion, $H_3$ and $H_4$ coefficients along three axes, and line-strength index profiles of Mg, Fe and H$\beta$.
Auger, Auger, Baggett, Beifiori, Bender, Bernardi, Bertola, Binney, Blanton, Cappellari, Clarke, Colless, Conroy, Corsini, Cox, Dalcanton, de Vaucouleurs, E. M. Corsini, G. A. Wegner, Gerhard, Gerhard, Gnedin, Gnedin, González, Gorgas, Graves, Hilz, Hoffman, Hopkins, Hopkins, J. Thomas, Koopmans, Kormendy, Lauer, Lynden-Bell, Markwardt, Martini, McMaster, Mehlert, Moré, Naab, Nakamura, Napolitano, Neill, Nelan, Osterbrock, Persic, Persic, R. Bender, R. P. Saglia, S. B. Pu, Saglia, Saglia, Sato, Struble, Thomas, Thomas, Treu, van Dokkum, Wechsler, Wegner, Wegner, Worthey   +62 more
core   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Suggestions for Escaping the Dark Ages for Pediatric Diffuse Intrinsic Pontine Glioma Treated with Radiotherapy: Analysis of Prognostic Factors from the National Multicenter Study. [PDF]

Cancer Res Treat, 2023
Kim HJ, Lee JH, Kim Y, Lim DH, Park SH, Ahn SD, Kim IA, Im JH, Chung JW, Kim JY, Kim IH, Yoon HI, Suh CO.   +12 more
europepmc   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Recovering 21cm Monopole Signals Without Smoothness

The Open Journal of Astrophysics
We expect the monopole signal at the lowest frequencies below $100\,$MHz to be composed to two components: the deep Rayleigh-Jeans tail of the cosmic microwave background and two distinct features: the dark ages trough at $\sim 17\,$MHz and the cosmic ...
Rugved Pund, Anže Slosar, Aaron Parsons
doaj   +1 more source

Dark-ages reionization & galaxy formation simulation IV: UV luminosity functions of high-redshift galaxies

, 2016
In this paper we present calculations of the UV luminosity function from the Dark-ages Reionization And Galaxy-formation Observables from Numerical Simulations (DRAGONS) project, which combines N-body, semi-analytic and semi-numerical modelling designed ...
Angel, P. W., Duffy, Alan R., Geil, Paul M., Liu, Chuanwu, Mesinger, Andrei, Mutch, Simon J., Poole, Gregory B., Wyithe, J. Stuart B.   +7 more
core   +1 more source