Results 91 to 100 of about 727,203 (295)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Alleviation of Cosmic Age Problem In Interacting Dark Energy Model

open access: yes, 2008
We investigate the cosmic age problem associated with the old high-$z$ quasar APM 08279 + 5255 and the oldest globular cluster M 107, both being difficult to accommodate in $\Lambda$CDM model.
Alcaniz   +70 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

SPECTACLE OVER SUBSTANCE: THE DIGITAL APPROACH OF DARK TOURISM [PDF]

open access: yesAnnals of the University of Oradea: Economic Science
In nowadays digital era, sites of trauma, death, disasters and collective mourning are highly mediated through online platform designed for entertainment and visibility, all empowered by algorithms.
Ioana FEICA-PRODAN
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

Probing Small-scale Dark Matter Clumping with the Large-scale 21 cm Power Spectrum

open access: yesThe Astrophysical Journal Letters
The 21 cm line of hydrogen is the most promising probe of the Dark Ages and Cosmic Dawn. We combine hydrodynamical simulations with a large-scale grid in order to calculate the effect of nonlinear structure formation on the large-scale 21 cm power ...
Sudipta Sikder   +4 more
doaj   +1 more source

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