Results 81 to 90 of about 1,465,941 (244)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Dark Energy in the Dark Ages [PDF]
, 2009 Non-negligible dark energy density at high redshifts would indicate dark energy physics distinct from a cosmological constant or "reasonable'" canonical scalar fields.
Linder, Eric V.
core
, 2023 Dark matter lighter than 10 GeV=c2 encompasses a promising range of candidates. A conceptual design for a new detector, DarkSide-LowMass, is presented, based on the DarkSide-50 detector and progress toward DarkSide-20k, optimized for a low-threshold ...
G. Paternoster +2 more
core +1 more source
The Cosmic Dark Ages (Free Astronomy Public Lectures)
, 2010 How did the elements come into existence, and how we can use them to count the number of stars in the early Universe?
Emma Ryan-Weber
core +1 more source
Astronomy & AstrophysicsContext. The 21cm–galaxy cross-correlations are expected to play a key role in the confirmation of the cosmological 21cm signal. Aims. We investigate which survey configurations detect the 21cm–Lyman-α emitter (LAE) cross-correlation signal and assess ...
Hutter Anne, Heneka Caroline
doaj +1 more source
Applying collaborative brain power to pull us out of the dark ages of pediatric neuro-oncology. [PDF]
Neoplasia, 2023 Koschmann C, Prados M.
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Before its time: A remarkably evolved protocluster core at z = 7.88
Astronomy & AstrophysicsProtoclusters represent the most extreme environments in the very early Universe. They form from large-scale dark matter overdensities, harbouring an overabundance of galaxies fed by large gas reservoirs.
Witten Callum +13 more
doaj +1 more source
Preface: Cardiorenal Considerations for Type 2 Diabetes-Time to Exit the Dark Ages. [PDF]
Diabetes Spectr, 2021 DeFronzo RA, Editor G.
europepmc +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source