Results 71 to 80 of about 1,465,941 (244)
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Astronomy & AstrophysicsThe progenitors of present-day galaxy clusters offer crucial insight into how galaxies and large-scale structure co-evolve in the early Universe. We present JWST/NIRCam grism spectroscopy of the photometrically identified z = 7.66 protocluster core in ...
Witten Callum +7 more
doaj +1 more source
Britain in the Seventies – Our Unfinest Hour?
Revue Française de Civilisation Britannique, 2017 In popular recollection, the 1970s have gone down as the dark ages, Britain’s gloomiest period since the second world war, set between Harold Wilson’s ‘swinging sixties’ and Margaret Thatcher’s divisive eighties. Forty years on, it is appropriate for the
Kenneth O. Morgan
doaj +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Dark ages, a window on the dark sector. Hunting for ultra-light axions [PDF]
Measurements of 21 cm intensity mapping (IM) during the dark ages can potentially provide us with an unprecedented window on high redshifts and small scales.
Vanzan, Eleonora +2 more
core +1 more source
Dark Energy And Life's Ultimate Future [PDF]
, 2006 The discovery of the present accelerated expansion of space changed everything regarding cosmology and life's ultimate prospects. Both the optimistic scenarios of an ever (but decelerated) expanding universe and of a collapsing universe seem to be no ...
Ruediger Vaas, Vaas, Ruediger
core +1 more source
Sensitivity of the Hongmeng 21 cm experiment to scattering dark matter
Astronomy & AstrophysicsScattering between dark matter and baryons can cool the intergalactic medium temperature and deepen the 21 cm signal. Such interactions have been proposed to explain the unusually deep 21 cm absorption signal reported by EDGES in 2018.
Cang Junsong, Gao Yu, Ma Yin-Zhe
doaj +1 more source
The R/renaissance(s), Humanists And Classics
The Journal of Classics Teaching, 2018 First, where does the Renaissance fit in chronologically with other periods of the past? There is general agreement that the Renaissance should be dated from 1300 to 1650, though some believe that a more accurate and meaningful starting date would be ...
Jerome Moran
doaj +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source