Results 51 to 60 of about 116,847 (299)

Establishing a relationship between the cosmological 21 cm power spectrum and interferometric closure phases

Astronomy & Astrophysics
Context. Measurements of the cosmic 21 cm background need to achieve a high dynamic range to isolate it from bright foreground emissions. Instrumental calibration inaccuracies can compromise the spectral fidelity of the smooth foreground continuum ...
Keller P. M., Nikolic B., Thyagarajan N.
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Before its time: A remarkably evolved protocluster core at z = 7.88

Astronomy & Astrophysics
Protoclusters represent the most extreme environments in the very early Universe. They form from large-scale dark matter overdensities, harbouring an overabundance of galaxies fed by large gas reservoirs.
Witten Callum, Oesch Pascal A., McClymont William, Meyer Romain A., Fudamoto Yoshinobu, Sijacki Debora, Laporte Nicolas, Bennett Jake S., Simmonds Charlotte, Giovinazzo Emma, Danhaive A. Lola, Ciesla Laure, Carvajal-Bohorquez Cristian, Trebitsch Maxime   +13 more
doaj   +1 more source

The development of the Church of St Mary at Ephesos from late antiquity to the Dark Ages

, 2019
The Church of St Mary is one of the most significant monuments of Ephesos, but also one of the most enigmatic. Its repeated modifications prior to its destruction created an amalgam of different phases that have proven difficult to decipher within the ...
Karydis, Nikolaos
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Constraining reionization morphology and source properties with 21 cm galaxy cross-correlation surveys

Astronomy & Astrophysics
Cross-correlations between 21 cm observations and galaxy surveys provide a powerful probe of reionization by providing robustness against foreground contamination while linking ionization morphology to galaxies. We quantified the constraining power of 21
Pietschke Yannic, Hutter Anne, Heneka Caroline   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Dark-ages reionization and galaxy formation simulation - IV. UV luminosity functions of high-redshift galaxies

, 2016
In this paper, we present calculations of the UV luminosity function (LF) from the Dark-ages Reionization And Galaxy-formation Observables from Numerical Simulations project, which combines N-body, semi-analytic and seminumerical modelling designed to ...
Alan Duffy (18925381), Simon J. Mutch (19005473), P. W. Angel (19015055), Paul M. Geil (19010342), Gregory B. Poole (18999008), Chuanwu Liu (19015052), Andrei Mesinger (16164626), J. Stuart B Wyithe (19015049)   +7 more
core   +1 more source

Public Archaeology for the Dark Ages

, 2020
This introductory chapter identifies the principal issues and themes in the public archaeology of the Early Middle Ages, exploring the specific and compelling challenges of investigating and evaluating the early medieval past in contemporary society ...
Williams, Howard, Howard Williams
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source