Results 61 to 70 of about 112,066 (261)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Measuring the intergalactic medium correlation length at 5 < z < 6.1: A fast change at the end of reionization

Astronomy & Astrophysics
Context. The Lyman-α forest of high-redshift quasars is a powerful probe of the late stages of the epoch of reionization (EoR), in particular thanks to the presence of Gunn-Peterson troughs.
Spina Benedetta, Bosman Sarah E. I., Maity Barun, Davies Frederick B.   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Establishing a relationship between the cosmological 21 cm power spectrum and interferometric closure phases

Astronomy & Astrophysics
Context. Measurements of the cosmic 21 cm background need to achieve a high dynamic range to isolate it from bright foreground emissions. Instrumental calibration inaccuracies can compromise the spectral fidelity of the smooth foreground continuum ...
Keller P. M., Nikolic B., Thyagarajan N.
doaj   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

Constraining reionization morphology and source properties with 21 cm galaxy cross-correlation surveys

Astronomy & Astrophysics
Cross-correlations between 21 cm observations and galaxy surveys provide a powerful probe of reionization by providing robustness against foreground contamination while linking ionization morphology to galaxies. We quantified the constraining power of 21
Pietschke Yannic, Hutter Anne, Heneka Caroline   +2 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

PRISMS: U37126, a very blue ISM-naked starburst at z = 10.255 with a nearly 100% Lyman continuum escape fraction

Astronomy & Astrophysics
We present very deep (≈11 hours on-source) JWST/MIRI low-resolution spectroscopy of the rest-frame optical emission of U37126, a UV-bright (MUV ≃ −20) mildly lensed (μ ≃ 2.2) galaxy at z = 10.255.
Marques-Chaves R., Álvarez-Márquez J., Colina L., Kendrew S., Abdurro’uf, Blanco-Prieto C., Boogaard L. A., Castellano M., Caputi K. I., Crespo-Gómez A., Fontana A., Fudamoto Y., Fujimoto S., García-Marín M., Harikane Y., Harish S., Hashimoto T., Hsiao T., Iani E., Inoue A. K., Langeroodi D., Lin R., Melinder J., Napolitano L., Östlin G., Pérez-González P. G., Prieto-Jiménez C., Rinaldi P., Rodríguez Del Pino B., Santini P., Sugahara Y., Varo-O’Ferrall A., Wright G., Zavala J.   +33 more
doaj   +1 more source

GUY HALSALL, WORLDS OF ARTHUR. FACTS AND FICTIONS OF THE DARK AGES

Journal of Ancient History and Archaeology, 2015
Guy Halsall, Worlds of Arthur. Facts and Fictions of the Dark Ages, Oxford: University Press, 2014. 384 pp.
Vlad Andrei Lazarescu
doaj   +1 more source

Applying collaborative brain power to pull us out of the dark ages of pediatric neuro-oncology. [PDF]

Neoplasia, 2023
Koschmann C, Prados M.
europepmc   +1 more source