Results 61 to 70 of about 1,722,078 (332)

Braneworlds and dark energy [PDF]

Journal of Physics A: Mathematical and General, 2006
12 pages, latex, 3 eps figures. Talk given at the Seventh Workshop on Quantum Field Theory under the Influence of External Conditions, IEEC, CSIC and University of Barcelona, Barcelona, Catalonia, Spain, 5-9 September 2005. Revised version published in the workshop proceedings, J. Phys. A: Mathematical and General.
Rui Neves, Rui Neves, Cenalo Vaz
openaire   +4 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Chameleon Dark Energy

, 2004
Chameleons are scalar fields whose mass depends on the environment, specifically on the ambient matter density. While nearly massless in the cosmos, where the matter density is tiny, their mass is of order of an inverse millimeter on Earth, where the ...
Brax, Ph., Davis, A. C., Khoury, J., van de Bruck, C., Weltman, A.   +4 more
core   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Coupling q-Deformed Dark Energy to Dark Matter

Advances in High Energy Physics, 2016
We propose a novel coupled dark energy model which is assumed to occur as a q-deformed scalar field and investigate whether it will provide an expanding universe phase. We consider the q-deformed dark energy as coupled to dark matter inhomogeneities.
Emre Dil
doaj   +1 more source

Pilgrim Dark Energy

, 2012
In the present work, we reconsider the idea of holographic dark energy. One of its key points is the formation of the black hole. And then, we propose the so-called "pilgrim dark energy" based on the speculation that the repulsive force contributed by ...
Wei, Hao
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Quantum Haplodynamics, Dark Matter, and Dark Energy

Advances in High Energy Physics, 2014
In quantum haplodynamics (QHD) the weak bosons, quarks, and leptons are bound states of fundamental constituents, denoted as haplons. The confinement scale of the associated gauge group SU(2)h is of the order of Λh≃0.3 TeV.
Harald Fritzsch, Joan Solà
doaj   +1 more source

The Growth of Structure in Interacting Dark Energy Models [PDF]

, 2009
If dark energy interacts with dark matter, there is a change in the background evolution of the universe, since the dark matter density no longer evolves as a^{-3}. In addition, the non-gravitational interaction affects the growth of structure.
Caldera-Cabral, Gabriela, Maartens, Roy, Schaefer, Bjoern Malte   +2 more
core   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source