Results 71 to 80 of about 500,277 (262)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Old dark energy [PDF]

open access: yesPhysical Review D, 2010
Dark energy dynamics in the recent universe is influenced by its evolution through the long, matter dominated expansion history. A particular dynamical property, the flow variable, remains constant in several classes of scalar field models as long as matter dominates; the dark energy is only free to diverge in behavior at recent times.
Cortês, Marina, Linder, Eric V.
openaire   +2 more sources

Astrometric Redshifts of Supernovae

open access: yesThe Astrophysical Journal
Differential Chromatic Refraction (DCR) is caused by the wavelength dependence of our atmosphere’s refractive index, which shifts the apparent positions of stars and galaxies and distorts their shapes depending on their spectral energy distributions ...
Jaemyoung (Jason) Lee   +4 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Dark energy and the MSSM

open access: yesPhysical Review D, 2007
We consider the coupling of quintessence to observable matter in supergravity and study the dynamics of both supersymmetry breaking and quintessence in this context. We investigate how the quintessence potential is modified by supersymmetry breaking and analyse the structure of the soft supersymmetry breaking terms. We pay attention to their dependence
Brax, Philippe, Martin, Jérôme
openaire   +2 more sources

Bouncing Cosmologies with Dark Matter and Dark Energy

open access: yesUniverse, 2016
We review matter bounce scenarios where the matter content is dark matter and dark energy. These cosmologies predict a nearly scale-invariant power spectrum with a slightly red tilt for scalar perturbations and a small tensor-to-scalar ratio. Importantly,
Yi-Fu Cai   +3 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Testing the Interacting Dark Energy Model with Cosmic Microwave Background Anisotropy and Observational Hubble Data

open access: yesEntropy, 2017
The coupling between dark energy and dark matter provides a possible approach to mitigate the coincidence problem of the cosmological standard model. In this paper, we assumed the interacting term was related to the Hubble parameter, energy density of ...
Weiqiang Yang   +4 more
doaj   +1 more source

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