Results 61 to 70 of about 500,277 (262)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Scattering of dark matter and dark energy [PDF]
Physical Review D, 2010 5 pages, 4 figures, minor changes reflect published ...
openaire +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Physics Letters BThe 12C+12C fusion reaction at deep subbarrier energies is important for understanding the carbon burning process in massive star and explosive binary systems.
Weike Nan +19 more
doaj +1 more source
Improvement of airfoil trailing edge bluntness noise model
Advances in Mechanical Engineering, 2016 In this article, airfoil trailing edge bluntness noise is investigated using both computational aero-acoustic and semi-empirical approach. For engineering purposes, one of the most commonly used prediction tools for trailing edge noise are based on semi ...
Wei Jun Zhu +3 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Coupling q-Deformed Dark Energy to Dark Matter
Advances in High Energy Physics, 2016 We propose a novel coupled dark energy model which is assumed to occur as a q-deformed scalar field and investigate whether it will provide an expanding universe phase. We consider the q-deformed dark energy as coupled to dark matter inhomogeneities.
Emre Dil
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Dark Matter and Dark Energy in the Universe
Bibechana, 2014 Cosmological and astronomical observations predict that the present Universe is passing through an accelerating phase of expansion. The Universe emerged out of an exponential phase in the very early Universe.
BC Paul
doaj +3 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Quantum Haplodynamics, Dark Matter, and Dark Energy
Advances in High Energy Physics, 2014 In quantum haplodynamics (QHD) the weak bosons, quarks, and leptons are bound states of fundamental constituents, denoted as haplons. The confinement scale of the associated gauge group SU(2)h is of the order of Λh≃0.3 TeV.
Harald Fritzsch, Joan Solà
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