Results 81 to 90 of about 6,544,802 (296)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The clustering of dark matter, haloes & galaxies [PDF]

open access: yes, 2008
In this thesis I study the spatial distribution of galaxies, haloes and dark matter particles using a suite of state-of-art cosmological N-body simulations of the growth structure in the Universe.
Angulo de la Fuente, Raúl Esteban
core  

Determination of resonances in Gamow window for 12C+12C fusion reaction via thick-target inverse kinematics method

open access: yesPhysics Letters B
The 12C+12C fusion reaction at deep subbarrier energies is important for understanding the carbon burning process in massive star and explosive binary systems.
Weike Nan   +19 more
doaj   +1 more source

Improvement of airfoil trailing edge bluntness noise model

open access: yesAdvances in Mechanical Engineering, 2016
In this article, airfoil trailing edge bluntness noise is investigated using both computational aero-acoustic and semi-empirical approach. For engineering purposes, one of the most commonly used prediction tools for trailing edge noise are based on semi ...
Wei Jun Zhu   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Optimizing New Dark Energy Experiments [PDF]

open access: yes, 2013
Next generation “Stage IV” dark energy experiments under design during this grant, and now under construction, will enable the determination of the properties of dark energy and dark matter to unprecedented precision using multiple complementary probes ...
Tyson, J. Anthony
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Dark Matter and Dark Energy in the Universe

open access: yesBibechana, 2014
Cosmological and astronomical observations predict that the present Universe is passing through an accelerating phase of expansion. The Universe emerged out of an exponential phase in the very early Universe.
BC Paul
doaj   +3 more sources

Coupling q-Deformed Dark Energy to Dark Matter

open access: yesAdvances in High Energy Physics, 2016
We propose a novel coupled dark energy model which is assumed to occur as a q-deformed scalar field and investigate whether it will provide an expanding universe phase. We consider the q-deformed dark energy as coupled to dark matter inhomogeneities.
Emre Dil
doaj   +1 more source

Dark energy and the MSSM

open access: yesPhysical Review D, 2007
We consider the coupling of quintessence to observable matter in supergravity and study the dynamics of both supersymmetry breaking and quintessence in this context. We investigate how the quintessence potential is modified by supersymmetry breaking and analyse the structure of the soft supersymmetry breaking terms. We pay attention to their dependence
Brax, Philippe, Martin, Jérôme
openaire   +2 more sources

Home - About - Disclaimer - Privacy