Results 71 to 80 of about 685,566 (247)
Mono-lepton signature of a neutrino-philic dark fermion at hadron colliders
Nuclear Physics BSearching for dark matter at high-energy colliders and direct detection experiments can effectively cover nearly the entire mass range from the MeV to the TeV scale.
Kai Ma, Lin-Yun He
doaj +1 more source
Indirect searches for dark matter bound state formation and level transitions
SciPost Physics, 2020 Indirect searches for dark matter (DM) have conventionally been applied to the products of DM annihilation or decay. If DM couples to light force carriers, however, it can be captured into bound states via dissipation of energy that may yield ...
Iason Baldes, Francesca Calore, Kalliopi Petraki, Vincent Poireau, Nicholas L. Rodd
doaj +1 more source
TESTING THE DARK-ENERGY-DOMINATED COSMOLOGY BY THE SOLAR-SYSTEM EXPERIMENTS [PDF]
The Eleventh Marcel Grossmann Meeting, 2008 According to the recent astronomical data, the most part of energy in the Universe is in the 'dark' form, which is effectively described by Lambda-term in Einstein equations. All arguments in favor of the dark energy were obtained so far from the observational data related to very large (intergalactic) scales.
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Scattering meets absorption in dark matter detection
Journal of High Energy PhysicsDirect detection experiments have started to explore dark matter scattering off electrons and nucleons through light mediators. Mediators with sub-keV masses are efficiently produced in the Sun and can be absorbed in the same detectors that probe dark ...
Pieter Braat +3 more
doaj +1 more source
Experimental implications of mirror matter-type dark matter
, 2003 Mirror matter-type dark matter is one dark matter candidate which is particularly well motivated from high energy physics. The theoretical motivation and experimental evidence are pedagogically reviewed, with emphasis on the implications of recent ...
Berezhiani Z. +11 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Dark Energy and Neutrino CPT Violation
, 2007 In this paper we study the dynamical CPT violation in the neutrino sector induced by the dark energy of the Universe. Specifically we consider a dark energy model where the dark energy scalar derivatively interacts with the right-handed neutrinos.
A. Datta +67 more
core +1 more source
Experimental identification of non-pointlike dark-matter candidates [PDF]
, 2002 We show that direct dark matter detection experiments can distinguish between pointlike and non-pointlike dark-matter candidates. The shape of the nuclear recoil energy spectrum from pointlike dark-matter particles, e.g., neutralinos, is determined by ...
A. Anisimov +15 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source