Results 91 to 100 of about 1,660,126 (341)
Acta Physica Polonica B, 2013 We study the scenario where dark matter corresponds to a set of pseudo-Goldstone bosons, that we call dark pions, generated by the spontaneous breaking of a symmetry in the dark sector. As a concrete example, we consider an SU(N) SU(N) broken to the diagonal subgroup that remains an exact symmetry that ensures the stability of the dark pions, and ...
Bhattacharya, S., Melić, B., Wudka, J.
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
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The Astrophysical Journal, 2007 4 pages, 4 figures, emulateapj.cls; Astrophysical Journal Letters ...
Moskalenko, Igor V. +2 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
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CYG $$\nu $$ ν S: detecting solar neutrinos with directional gas time projection chambers
European Physical Journal C: Particles and FieldsCygnus is a proposed global network of large-scale gas time projection chambers (TPCs) with the capability of directionally detecting nuclear and electron recoils at $$\gtrsim $$ ≳ keV energies.
Chiara Lisotti +10 more
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
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The Macronova in GRB 050709 and the GRB-macronova connection
Nature Communications, 2016 A macronova is a clear signature that a short gamma-ray burst has been emitted by a compact-binary merger, but evidence of these events is so far scarce.
Zhi-Ping Jin +8 more
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Tsallis cosmology and its applications in dark matter physics with focus on IceCube high-energy neutrino data [PDF]
, 2022 Petr Jizba, Gaetano Lambiase
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
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Charmed baryon decays: SU(3) F breaking and CP violation
Journal of High Energy PhysicsWe present a comprehensive study of anti-triplet charmed baryon decays into octet baryons and pseudoscalar mesons using the SU(3) F flavor symmetry framework.
Chang Yang, Xiao-Gang He, Chia-Wei Liu
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