Results 71 to 80 of about 1,630,167 (297)

DARK MATTER AXIONS [PDF]

International Journal of Modern Physics A, 1994
The hypothesis of an 'invisible' axion was made by Misha Shifman and others, approximately thirty years ago. It has turned out to be an unusually fruitful idea, crossing boundaries between particle physics, astrophysics and cosmology. An axion with mass of order 10-5 eV (with large uncertainties) is one of the leading candidates for the dark matter of
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Probing dark matter particles at CEPC

, 2019
We investigate the capability of the future electron collider CEPC in probing the parameter space of several dark matter models, including millicharged dark matter models, $Z'$ portal dark matter models, and effective field theory dark matter models.
Liu, Zuowei, Xu, Yong-Heng, Zhang, Yu
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Unexpected major geomagnetic storm caused by faint eruption of a solar trans-equatorial flux rope

Nature Communications
Some geomagnetic storms’ solar origins are ambiguous, making them hard to predict. On March 23, 2023, a severe geomagnetic storm occurred, however, forecasts based on remote-sensing observations failed to predict it.
Weilin Teng, Yingna Su, Haisheng Ji, Qingmin Zhang   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A delayed 400 GeV photon from GRB 221009A and implication on the intergalactic magnetic field

Nature Communications
Large High Altitude Air Shower Observatory has detected 0.2 − 13 TeV emission of GRB 221009A within 2000 s since the trigger. Here we report the detection of a 400 GeV photon, without accompanying prominent low-energy emission, by Fermi Large Area ...
Zi-Qing Xia, Yun Wang, Qiang Yuan, Yi-Zhong Fan   +3 more
doaj   +1 more source

DARK ENERGY, DARK MATTER AND GRAVITY [PDF]

International Journal of Modern Physics D, 2007
We discuss the motivation for high accuracy relativistic gravitational experiments in the solar system and complementary cosmological tests. We focus our attention on the issue of distinguishing a generic scalar theory of gravity as the underlying physical theory from the usual general-relativistic picture, where one expects the presence of ...
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Classification of three-family flavoured DFSZ axion models that have no domain wall problem

Journal of High Energy Physics
We provide an exhaustive classification of three-family DFSZ axion models that have no cosmological domain wall problem. This result is obtained by making the Peccei-Quinn symmetry flavour dependent in certain specific ways, thus reinforcing a possible ...
Peter Cox, Matthew J. Dolan, Maaz Hayat, Andrea Thamm, Raymond R. Volkas   +4 more
doaj   +1 more source