Results 51 to 60 of about 214,465 (268)

A delayed 400 GeV photon from GRB 221009A and implication on the intergalactic magnetic field

open access: yesNature Communications
Large High Altitude Air Shower Observatory has detected 0.2 − 13 TeV emission of GRB 221009A within 2000 s since the trigger. Here we report the detection of a 400 GeV photon, without accompanying prominent low-energy emission, by Fermi Large Area ...
Zi-Qing Xia   +3 more
doaj   +1 more source

Effect of the pion field on the distributions of pressure and shear in the proton

open access: yesPhysics Letters B, 2022
In light of recent experimental progress in determining the pressure and shear distributions in the proton, these quantities are calculated in a model with confined quarks supplemented by the pion field required by chiral symmetry.
Shiryo Owa, A.W. Thomas, X.G. Wang
doaj   +1 more source

Fuzzy Dark Matter and Dark Matter Halo Cores [PDF]

open access: yesThe Astrophysical Journal, 2020
Abstract Whereas cold dark matter (CDM) simulations predict central dark matter cusps with densities that diverge as ρ(r) ∼  1/r, observations often indicate constant-density cores with finite central densities ρ 0 and a flat density distribution within a core radius r 0.
openaire   +3 more sources

Dark dimension gravitons as dark matter

open access: yesJournal of High Energy Physics, 2023
Abstract We consider cosmological aspects of the Dark Dimension (a mesoscopic dimension of micron scale), which has recently been proposed as the unique corner of the quantum gravity landscape consistent with both the Swampland criteria and observations.
Gonzalo, Eduardo   +3 more
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Classification of three-family flavoured DFSZ axion models that have no domain wall problem

open access: yesJournal of High Energy Physics
We provide an exhaustive classification of three-family DFSZ axion models that have no cosmological domain wall problem. This result is obtained by making the Peccei-Quinn symmetry flavour dependent in certain specific ways, thus reinforcing a possible ...
Peter Cox   +4 more
doaj   +1 more source

DARK MATTER AXIONS [PDF]

open access: yesInternational Journal of Modern Physics A, 1994
The hypothesis of an 'invisible' axion was made by Misha Shifman and others, approximately thirty years ago. It has turned out to be an unusually fruitful idea, crossing boundaries between particle physics, astrophysics and cosmology. An axion with mass of order 10-5 eV (with large uncertainties) is one of the leading candidates for the dark matter of
openaire   +2 more sources

BRANEWORLDS AND DARK MATTER [PDF]

open access: yesInternational Journal of Modern Physics D, 2011
Two problems related to dark matter are considered in the context of a braneworld model in which the confinement of gauge fields on the brane is achieved by invoking a confining potential. First, we show that the virial mass discrepancy can be addressed if the conserved geometrical term appearing in this model is considered as an energy–momentum ...
Shahidi, Shahab, Sepangi, Hamid Reza
openaire   +3 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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