Results 51 to 60 of about 217,256 (267)

Classification of three-family flavoured DFSZ axion models that have no domain wall problem

Journal of High Energy Physics
We provide an exhaustive classification of three-family DFSZ axion models that have no cosmological domain wall problem. This result is obtained by making the Peccei-Quinn symmetry flavour dependent in certain specific ways, thus reinforcing a possible ...
Peter Cox, Matthew J. Dolan, Maaz Hayat, Andrea Thamm, Raymond R. Volkas   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

DARK MATTER SEARCHES [PDF]

International Journal of Modern Physics A, 2006
More than 90% of matter in the Universe could be composed of heavy particles, which were non-relativistic, or 'cold', when they froze-out from the primordial soup. I will review current searches for these hypothetical particles, both via interactions with nuclei in deep underground detectors, and via the observation of their annihilation products in ...
openaire   +5 more sources

Effect of the pion field on the distributions of pressure and shear in the proton

Physics Letters B, 2022
In light of recent experimental progress in determining the pressure and shear distributions in the proton, these quantities are calculated in a model with confined quarks supplemented by the pion field required by chiral symmetry.
Shiryo Owa, A.W. Thomas, X.G. Wang
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Fuzzy Dark Matter and Dark Matter Halo Cores [PDF]

The Astrophysical Journal, 2020
Abstract Whereas cold dark matter (CDM) simulations predict central dark matter cusps with densities that diverge as ρ(r) ∼  1/r, observations often indicate constant-density cores with finite central densities ρ 0 and a flat density distribution within a core radius r 0.
openaire   +3 more sources

Dark dimension gravitons as dark matter

Journal of High Energy Physics, 2023
Abstract We consider cosmological aspects of the Dark Dimension (a mesoscopic dimension of micron scale), which has recently been proposed as the unique corner of the quantum gravity landscape consistent with both the Swampland criteria and observations.
Gonzalo, Eduardo, Montero, Miguel, Obied, Georges, Vafa, Cumrun   +3 more
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

DARK MATTER AXIONS [PDF]

International Journal of Modern Physics A, 1994
The hypothesis of an 'invisible' axion was made by Misha Shifman and others, approximately thirty years ago. It has turned out to be an unusually fruitful idea, crossing boundaries between particle physics, astrophysics and cosmology. An axion with mass of order 10-5 eV (with large uncertainties) is one of the leading candidates for the dark matter of
openaire   +2 more sources

BRANEWORLDS AND DARK MATTER [PDF]

International Journal of Modern Physics D, 2011
Two problems related to dark matter are considered in the context of a braneworld model in which the confinement of gauge fields on the brane is achieved by invoking a confining potential. First, we show that the virial mass discrepancy can be addressed if the conserved geometrical term appearing in this model is considered as an energy–momentum ...
Shahidi, Shahab, Sepangi, Hamid Reza
openaire   +3 more sources