Results 111 to 120 of about 1,667,560 (344)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Dark branes for dark matter

open access: yesPhysical Review D
We propose a setup for the origin of dark matter based on spacetime with a warped extra dimension and three branes: the Planck brane, the TeV brane, at a (few) TeV scale ρT, and a dark brane, at a (sub-)GeV scale ρ1≲100  GeV≪ρT. The Standard Model (SM) is localized in the TeV brane, thus solving the Higgs hierarchy problem, while the dark matter χ, a ...
Fotis Koutroulis   +3 more
openaire   +2 more sources

Anapole dark matter

open access: yesPhysics Letters B, 2013
7 pages, 5 figures, v3: version to appear in ...
Ho, Chiu Man, Scherrer, Robert J.
openaire   +2 more sources

Asymmetric capture of Dirac dark matter by the Sun

open access: yes, 2015
Current problems with the solar model may be alleviated if a significant amount of dark matter from the galactic halo is captured in the Sun. We discuss the capture process in the case where the dark matter is a Dirac fermion and the background halo ...
Blennow, Mattias, Clementz, Stefan
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Exploring sub-GeV dark matter physics with cosmic ray and future telescopes

open access: yesEuropean Physical Journal C: Particles and Fields
If sub-GeV dark matter (DM) annihilates into charged particles such as $$e^+ e^-$$ e + e - , $$\mu ^+ \mu ^-$$ μ + μ - , or $$\pi ^+ \pi ^-$$ π + π - , it generates an additional source of electrons and positrons in the cosmic ray (CR) population within ...
Guan-Sen Wang   +3 more
doaj   +1 more source

Review of Observational Evidence for Dark Matter in the Universe and in upcoming searches for Dark Stars

open access: yes, 2008
Over the past decade, a consensus picture has emerged in which roughly a quarter of the universe consists of dark matter. The observational evidence for the existence of dark matter is reviewed: rotation curves of galaxies, weak lensing measurements, hot
Abel   +38 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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