Results 121 to 130 of about 4,173,231 (371)

Dark Matter "Collider" from Inelastic Boosted Dark Matter

open access: yes, 2016
We propose a novel dark matter (DM) detection strategy for the models with non-minimal dark sector. The main ingredients in the underlying DM scenario are a boosted DM particle and a heavier dark sector state.
Kim, Doojin   +2 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

The ScotoSinglet Model: a scalar singlet extension of the Scotogenic Model

open access: yesJournal of High Energy Physics, 2021
The Scotogenic Model is one of the most minimal models to account for both neutrino masses and dark matter (DM). In this model, neutrino masses are generated at the one-loop level, and in principle, both the lightest fermion singlet and the lightest ...
Ankit Beniwal   +4 more
doaj   +1 more source

Direct detection of strongly interacting sub-GeV dark matter via electron recoils [PDF]

open access: yesJournal of Cosmology and Astroparticle Physics, 2019
We consider direct-detection searches for sub-GeV dark matter via electron scatterings in the presence of large interactions between dark and ordinary matter.
T. Emken   +3 more
semanticscholar   +1 more source

A New Direction in Dark-Matter Complementarity: Dark-Matter Decay as a Complementary Probe of Multi-Component Dark Sectors

open access: yes, 2015
In single-component theories of dark matter, the $2\to 2$ amplitudes for dark-matter production, annihilation, and scattering can be related to each other through various crossing symmetries.
Dienes, Keith R.   +3 more
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

CYG $$\nu $$ ν S: detecting solar neutrinos with directional gas time projection chambers

open access: yesEuropean Physical Journal C: Particles and Fields
Cygnus is a proposed global network of large-scale gas time projection chambers (TPCs) with the capability of directionally detecting nuclear and electron recoils at $$\gtrsim $$ ≳ keV energies.
Chiara Lisotti   +10 more
doaj   +1 more source

Hidden Hot Dark Matter as Cold Dark Matter [PDF]

open access: yes, 2009
We show that hidden hot dark matter, hidden-sector dark matter with interactions that decouple when it is relativistic, is a viable dark matter candidate provided it has never been in thermal equilibrium with the particles of the standard model.
Sigurdson, Kris
core   +1 more source

Inflaxion dark matter [PDF]

open access: yesJournal of High Energy Physics, 2019
Abstract A new mechanism for producing axion dark matter is proposed. By invoking low-scale inflation and a kinetic mixing between the axion and the inflaton, it is shown that the axion is driven to a field point slightly displaced from the potential minimum, which can give rise to the observed dark matter abundance.
Kobayashi, T., Ubaldi, L.
openaire   +6 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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