Results 11 to 20 of about 12,809 (205)

Efficient decoy selection to improve virtual screening using machine learning models. [PDF]

open access: yesJ Cheminform
Machine learning models using protein-ligand interaction fingerprints show promise as target-specific scoring functions in drug discovery, but their performance critically depends on the underlying decoy selection strategies.
Victoria-Muñoz F   +3 more
europepmc   +2 more sources

DELight: A Direct search Experiment for Light dark matter with superfluid helium

open access: yesSciPost Physics Proceedings, 2023
To reach ultra-low detection thresholds necessary to probe unprecedentedly low Dark Matter masses, target material alternatives and novel detector designs are essential.
Belina von Krosigk, Klaus Eitel, Christian Enss, Torben Ferber, Loredana Gastaldo, Felix Kahlhoefer, Sebastian Kempf, Markus Klute, Sebastian Lindemann, Marc Schumann, Francesco Toschi, Kathrin Valerius
doaj   +1 more source

Astroparticle Constraints from Cosmic Reionization and Primordial Galaxy Formation

open access: yesUniverse, 2022
We derived astroparticle constraints in different dark matter scenarios that are alternatives to cold dark matter (CDM): thermal relic warm dark matter, WDM; fuzzy dark matter, ψDM; self-interacting dark matter, SIDM; sterile neutrino dark matter, νDM ...
Andrea Lapi   +6 more
doaj   +1 more source

From Images to Dark Matter: End-to-end Inference of Substructure from Hundreds of Strong Gravitational Lenses

open access: yesThe Astrophysical Journal, 2023
Constraining the distribution of small-scale structure in our universe allows us to probe alternatives to the cold dark matter paradigm. Strong gravitational lensing offers a unique window into small dark matter halos (
Sebastian Wagner-Carena   +6 more
doaj   +1 more source

Methods and Strategies to Uncover Coral-Associated Microbial Dark Matter

open access: yesmSystems, 2022
The vast majority of environmental microbes have not yet been cultured, and most of the knowledge on coral-associated microbes (CAMs) has been generated from amplicon sequencing and metagenomes.
Júnia Schultz   +5 more
doaj   +1 more source

Dark Matter with Genuine Spin-2 Fields

open access: yesUniverse, 2018
Gravity is the only force which is telling us about the existence of Dark Matter. I will review the idea that this must be the case because Dark Matter is nothing else than a manifestation of Gravity itself, in the guise of an additional, massive, spin-2
Federico R. Urban
doaj   +1 more source

Bouncing Cosmologies with Dark Matter and Dark Energy

open access: yesUniverse, 2016
We review matter bounce scenarios where the matter content is dark matter and dark energy. These cosmologies predict a nearly scale-invariant power spectrum with a slightly red tilt for scalar perturbations and a small tensor-to-scalar ratio. Importantly,
Yi-Fu Cai   +3 more
doaj   +1 more source

Dwarf Galaxies, MOND, and Relativistic Gravitation

open access: yesAdvances in Astronomy, 2010
MOND is a phenomenological modification of Newton's law of gravitation which reproduces the dynamics of galaxies, without the need for additional dark matter. This paper reviews the basics of MOND and its application to dwarf galaxies.
Arthur Kosowsky
doaj   +1 more source

Observational constraints on dark matter models

open access: yesSciPost Physics Lecture Notes
In this short course, which complements the lecture on Dark Matter alternatives, I provide concrete examples of how Dark Matter (DM) models can be tested, whether for generic DM properties, or specific scenarios.
Eric Armengaud
doaj   +1 more source

On Dark Matter and Dark Energy in CCC+TL Cosmology

open access: yesUniverse
Relaxing the temporal constancy constraint on coupling constants in an expanding universe results in Friedmann equations containing terms that may be interpreted as dark energy and dark matter.
Rajendra P. Gupta
doaj   +1 more source

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