Results 101 to 110 of about 22,137 (292)

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Indirect detection, direct detection, and collider detection cross-sections for a 70 GeV dark matter WIMP [PDF]

, 2022
Bailey Tallman, Alexandra Boone, Caden LaFontaine, Trevor Croteau, Quinn Ballard, Sabrina Hernandez, Spencer Ellis, Adhithya Vijayakumarm, Fiona Lopez, Samuel Apata, Jehu Martinez, Roland E. Allen   +11 more
openalex   +1 more source

Evaluating the Resistance of Bifacial Perovskite Photodetectors to Xenon Ion Irradiation

Advanced Science, EarlyView.
Bifacial perovskite photodetectors maintain high efficiency and stability after 231 MeV xenon ion irradiation. Key photodetector parameters remain nearly unchanged at low fluence (1010 nucleons cm−2) and show only moderate degradation at high fluence (1011 nucleons cm−2), highlighting their strong radiation tolerance and suitability for optoelectronic ...
Yerassyl Yerlanuly, Hryhorii P. Parkhomenko, Almaz R. Beisenbayev, Maxim V. Zdorovets, Annie Ng, Askhat N. Jumabekov   +5 more
wiley   +1 more source

Vector dark matter from the 5-dimensional representation of SU(2) L

Journal of High Energy Physics
The introduction of electroweak multiplets that transform under any representation of the standard SU(2) L gauge group suggests the existence of electrically neutral stable particles capable of serving as cold dark matter in the ΛCDM cosmological model ...
Patricio Escalona, Sebastián Acevedo, Paulo Areyuna, Gonzalo Benítez-Irarrázabal, Pablo Solar, Alfonso Zerwekh   +5 more
doaj   +1 more source

SUSY Tools for Dark Matter and at the Colliders

, 2010
With present and upcoming SUSY searches both directly, indirectly and at accelerators, the need for accurate calculations is large. We will here go through some of the tools available both from a dark matter point of view and at accelerators. For natural
Boudjema, Fawzi, Edsjo, Joakim, Gondolo, Paolo   +2 more
core   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Novel collider signatures in the type-I 2HDM+a model

Journal of High Energy Physics
The 2HDM+a model is one of the main models used in the interpretations of dark matter searches at the LHC. So far, all the 2HDM+a benchmarks considered by the ATLAS and CMS experiments are limited to a type-II Yukawa sector, in which the Higgs bosons A ...
Spyros Argyropoulos, Ulrich Haisch, Ilia Kalaitzidou   +2 more
doaj   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

Dark fluxes from electromagnetic cascades

Journal of High Energy Physics
We study dark sector production in electromagnetic (EM) cascades. This problem requires accurate simulations of Standard Model (SM) and dark sector processes, both of which impact angular and energy distributions of emitted particles that ultimately ...
Nikita Blinov, Patrick J. Fox, Kevin J. Kelly, Pedro A. N. Machado, Ryan Plestid   +4 more
doaj   +1 more source

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

Advanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang, Yihang Xiao, Yingxiao Gao, Mingxuan Wu   +3 more
wiley   +1 more source