Results 81 to 90 of about 22,137 (292)

Complex dark photon dark matter EFT

open access: yesJournal of High Energy Physics
We construct an effective field theory for complex Stueckelberg dark photon dark matter. Such an effective construction can be realized by writing down a complete set of operators up to dimension six built with the complex dark photon and Standard Model ...
Enrico Bertuzzo   +2 more
doaj   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

open access: yesAdvanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao   +11 more
wiley   +1 more source

Burn‐Safe Biodegradable Magnetocaloric Composites for Temperature‐Controlled Biomedical Applications

open access: yesAdvanced Science, EarlyView.
This work investigates a magnetocaloric (Mn,Fe)2(P,Si) compound tailored for precise, self‐regulating heating in biomedical use. With a Curie temperature tuned at 43 °C, it enables therapeutic activation without overheating. Encapsulation in a composite ensures controlled temperature rise under an alternating magnetic field (AMF), with high ...
Pornpawee Uliss   +8 more
wiley   +1 more source

Probing exotic long-lived particles from the prompt side using the CONTUR method

open access: yesJournal of High Energy Physics
A method to derive constraints on new physics models featuring exotic long-lived particles using detector-corrected measurements of prompt states is presented.
L. Corpe   +3 more
doaj   +1 more source

Top-philic Vector-Like Portal to Scalar Dark Matter

open access: yes, 2018
We investigate the phenomenology of scalar singlet dark matter candidates that couple dominantly to the Standard Model via a Yukawa interaction with the top quark and a colored vector-like fermion.
Colucci, Stefano   +5 more
core   +2 more sources

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

open access: yesAdvanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou   +9 more
wiley   +1 more source

Laser induced Compton scattering to dark matter in effective field theory

open access: yesJournal of High Energy Physics
The detection of light dark matter (DM) is a longstanding challenge in terrestrial experiments. High-intensity facilities with intense electromagnetic field may provide a plausible strategy to study strong-field particle physics and search for light DM ...
Kai Ma, Tong Li
doaj   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

open access: yesAdvanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir   +7 more
wiley   +1 more source

Single‐Position Peptide Clustering for Peptidomics Reveals Novel Disease Biomarkers and Dysregulated Proteolytic Characteristics

open access: yesAdvanced Science, EarlyView.
A novel amino acid (aa)‐score‐based single‐position peptide clustering strategy is developed for peptidomics, enabling precise profiling of protein proteolysis in plasma from β‐thalassemia cohort. The method identifies new aa position‐based peptide cluster biomarkers validated by heavy‐labeled peptides, visualizes aggregated changes, uncovers disease ...
Na Li   +13 more
wiley   +1 more source

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