Results 131 to 140 of about 7,204,887 (298)

Searching for Dark Structures: A Comparison of Weak-lensing Convergence Maps and Lensing-weighted Galaxy Density Maps

open access: yesThe Astrophysical Journal Supplement Series
We present the result of a comparison between the dark matter distribution inferred from weak gravitational lensing and the observed galaxy distribution to identify dark structures with a high dark-matter-to-galaxy density ratio.
Soojin Kim   +2 more
doaj   +1 more source

Dark Matter Benchmark Models for Early LHC Run-2 Searches: Report of the ATLAS/CMS Dark Matter Forum [PDF]

open access: yes, 2015
This document is the final report of the ATLAS-CMS Dark Matter Forum, a forum organized by the ATLAS and CMS collaborations with the participation of experts on theories of Dark Matter, to select a minimal basis set of dark matter simplified models that ...
Sarkar, Subir   +3 more
core  

Theoretical strategies for comparing dark matter searches [PDF]

open access: yes, 2022
The thesis discusses two semplified models describing the dark matter particle and the mediator of its interaction with the standard model, with a critical discussion of the validity of the effective theory in these two case studies.
Racco, Davide
core  

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Microhalos and dark matter detection [PDF]

open access: yes, 2020
Cosmological structure formation predicts that our galactic halo contains an enormous hierarchy of substructures and streams, the remnants of the merging hierarchy that began with tiny Earth mass microhalos.
Moore, Ben   +2 more
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Mechanical detectors of scalar dark matter

open access: yes, 2020
Singh, SwatiThe aim of this thesis is to present and discuss the use of mechanical devices for dark matter detection and characterize their viability as a dark matter detectors.
Stump, Russell A., III
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

The cosmological relevance of Fuzzy Dark Matter

open access: yes, 2023
reservedThe concordance model of cosmology, the so-called Lambda CDM model, shows some shortcomes. However, if the dark matter considered in the model is characterized by an extremely low mass, then some of the imperfection could be explained.
PANOZZO, LUCA
core  

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

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